Point-of-Care Testing

Principles and Clinical Applications

  • Peter B. Luppa
  • Ralf Junker

Table of contents

  1. Front Matter
    Pages I-XXX
  2. I Introduction

    1. Front Matter
      Pages 1-1
    2. Peter B. Luppa, Ralf Junker, Claus Langer
      Pages 3-7
    3. Ralf Junker, Astrid Petersmann, Peter B. Luppa
      Pages 9-17
    4. Peter B. Luppa
      Pages 19-25
  3. II Methodology and analytical techniques

    1. Front Matter
      Pages 27-27
    2. Andreas Bietenbeck
      Pages 29-36
    3. Peter B. Luppa, Günther Proll, Michael Imhoff, Theodor Koschinsky
      Pages 37-46
    4. Michael Spannagl, Dirk Peetz
      Pages 47-56
    5. Dorthe Kixmüller, Ralf Junker
      Pages 57-61
    6. Ralf Junker, Norbert Gässler
      Pages 63-68
    7. Peter B. Luppa, Ralf Junker, Ingolf Schimke, Enno Stürenburg
      Pages 69-79
    8. Enno Stürenburg, Norbert Gässler, Aline Schröder, Udo Reischl
      Pages 81-89
    9. Peter B. Luppa, Sandeep K. Vashist, John H. T. Luong
      Pages 91-100
  4. III Clinical applications

    1. Front Matter
      Pages 101-102
    2. Hans Günther Wahl, Theodor Koschinsky
      Pages 103-120
    3. Michael Imhoff, Theodor Koschinsky
      Pages 121-128
    4. Peter B. Luppa, Jan Martin, Philipp Deetjen
      Pages 129-143
    5. Dirk Peetz, Jürgen Koszielny, Michael Spannagl
      Pages 145-153
    6. Dorthe Kixmüller, Norbert Gässler, Ralf Junker
      Pages 155-158
    7. Evangelos Giannitsis, Ingolf Schimke, Peter B. Luppa, Dirk Peetz
      Pages 159-170
    8. Norbert Gässler, Harald Schlebusch, Peter B. Luppa
      Pages 181-192
    9. Enno Stürenburg, Frank Hufert
      Pages 193-202
    10. Walter Schaffartzik, Christian Müller, Tobias Lindner, Julia Searle, Martin Möckel
      Pages 203-217
    11. Norbert Gässler
      Pages 219-224
    12. Silvia Achtzehn, Holger Broich, Joachim Mester
      Pages 225-241
    13. Vanadin Seifert-Klauss
      Pages 243-248
  5. IV Legal and organizational framework

    1. Front Matter
      Pages 249-249
    2. Folker Spitzenberger, Claus Langer, Ulrich M. Gassner
      Pages 251-260
    3. Ulrich M. Gassner
      Pages 261-268
    4. Peter B. Luppa, Christoph Braun, Andreas Bietenbeck
      Pages 269-279
    5. Mario Plebani
      Pages 281-286
    6. Axel Kramer, Eva Gruner
      Pages 287-293
    7. Norbert Gässler, Ralf Junker, Claus Langer, Birgit Schäfer
      Pages 295-300
  6. V Areas of application

    1. Front Matter
      Pages 301-301
    2. Norbert Gässler, Peter B. Luppa, Andreas Bietenbeck, Astrid Petersmann, Alexander Pröbstl, Daniel Romann et al.
      Pages 303-312
    3. Ralf Junker, Hans Günther Wahl
      Pages 313-318
    4. Hannelore Rott, Theodor Koschinsky
      Pages 319-325
    5. Norbert Gässler, Andreas Bietenbeck, Gerhard Eiselen
      Pages 327-331
    6. Andreas Bietenbeck, Siegfried Jedamzik
      Pages 333-336
    7. Sandeep K. Vashist, Peter B. Luppa, John H. T. Luong
      Pages 337-342
  7. VI Quality assurance

    1. Front Matter
      Pages 343-343
    2. Peter Fraunberger, Sylvia Gruber, Franziska Amiet, Martin Fiedler, Michel Vaubourdolle, Benedict Beneteau-Burnat et al.
      Pages 345-374
  8. VII Development trends

    1. Front Matter
      Pages 411-411
    2. Sandeep K. Vashist, John H. T. Luong, Peter B. Luppa, Ralf Junker
      Pages 413-420
    3. Christina Rode-Schubert, Thomas Norgall, Andreas Bietenbeck
      Pages 421-431

About this book


The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. 

 Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient.

The idea of conventional

and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory.

The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT.

 From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are describ

ed as well as a survey of future technologies that are on the future horizon.

The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents.

Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.



clinical chemical analyses coagulation diagnostics diabetes diagnostics continuous monitoring quick tests

Editors and affiliations

  • Peter B. Luppa
    • 1
  • Ralf Junker
    • 2
  1. 1.Klinikum rechts der IsarMünchenGermany
  2. 2.Universitätsklinikum Schleswig-HolsteinKielGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag GmbH Germany, part of Springer Nature 2018
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-662-54496-9
  • Online ISBN 978-3-662-54497-6
  • Buy this book on publisher's site