Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin

Methodology and General Considerations

  • Nina Dragicevic
  • Howard I. Maibach

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Factors Influencing Percutaneous Drug Penetration

    1. Front Matter
      Pages 1-1
    2. Dominik Selzer, Ulrich F. Schaefer, Claus-Michael Lehr, Steffi Hansen
      Pages 3-25
    3. Wing Man Lau, Keng Wooi Ng
      Pages 35-44
    4. Jeffrey E. Grice, Hamid R. Moghimi, Elizabeth Ryan, Qian Zhang, Isha Haridass, Yousuf Mohammed et al.
      Pages 45-75
    5. V. R. Leite-Silva, Jeffrey E. Grice, Yousuf Mohammed, Hamid R. Moghimi, Michael S. Roberts
      Pages 77-93
    6. S. Kevin Li, William I. Higuchi
      Pages 119-136
  3. Methods for Measuring the Percutaneous Drug Penetration

    1. Front Matter
      Pages 151-151
    2. Donald M. Cropek, Pankaj Karande
      Pages 153-184
    3. Ulrich F. Schaefer, D. Selzer, S. Hansen, Claus-Michael Lehr
      Pages 185-203
    4. Jürgen Lademann, Sabine Schanzer, Heike Richter, Martina C. Meinke, Hans-Jürgen Weigmann, Alexa Patzelt
      Pages 205-214
    5. Stéphanie Briançon, Marie-Alexandrine Bolzinger, Yves Chevalier
      Pages 229-246
    6. Julia Covi-Schwarz, Victoria Klang, Claudia Valenta
      Pages 247-254
    7. Mukul A. Ashtikar, Daya D. Verma, Alfred Fahr
      Pages 255-281
    8. Claudine Piérard-Franchimont, Trinh Hermanns-Lê, Gérald E. Piérard
      Pages 303-307
  4. The Retardation of Percutaneous Drug Penetration

    1. Front Matter
      Pages 309-309
    2. Katharina Bohnenblust-Woertz, Christian Surber
      Pages 311-320
    3. Dominique Jasmin Lunter, Rolf Daniels
      Pages 321-333
  5. Current Status of Dermal and Transdermal Drug Delivery

  6. Safety Issues and Ethics in Studies on Dermal and Transdermal Delivery

    1. Front Matter
      Pages 367-367
    2. Yousuf H. Mohammed, Hamid R. Moghimi, Shereen A. Yousef, Navin C. Chandrasekaran, Césa R. Bibi, Sinduja C. Sukumar et al.
      Pages 369-391
  7. Back Matter
    Pages 405-414

About this book


Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists​.


Assessment of drug penetration enhancement Enhancement techniques Retardation of percutaneous penetration Skin permeation Transdermal drug delivery

Editors and affiliations

  • Nina Dragicevic
    • 1
  • Howard I. Maibach
    • 2
  1. 1.Apoteka “Beograd”BelgradeSerbia
  2. 2.San FranciscoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2017
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-662-53268-3
  • Online ISBN 978-3-662-53270-6
  • Buy this book on publisher's site