Autonomic Innervation of the Heart

Role of Molecular Imaging

  • Riemer H.J.A. Slart
  • René A. Tio
  • Philip H. Elsinga
  • Markus Schwaiger

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Irma Battipaglia, Gaetano A. Lanza
    Pages 1-12
  3. Carlo de Asmundis, Guy Van Camp, Pedro Brugada
    Pages 13-60
  4. James T. Thackeray, Jean N. DaSilva, Philip H. Elsinga
    Pages 87-109
  5. Dominique Le Guludec, Jacques Delforge, Frédéric Dollé
    Pages 111-135
  6. F. Michelle de Roo, Koen Hilgerink, Jos G. W. Kosterink, Gert Luurtsema, Herman J. Woerdenbag, Hendrikus H. Boersma
    Pages 137-159
  7. Riemer H. J. A. Slart, Peter van der Meer, René A. Tio, Dirk J. van Veldhuisen, Philip H. Elsinga
    Pages 235-253
  8. Juhani Knuuti
    Pages 255-262
  9. Arnold F. Jacobson, Jagat Narula
    Pages 263-288
  10. Ichiro Matsunari, Junichi Taki
    Pages 289-307
  11. Arthur J. H. A. Scholte, Hein J. Verberne
    Pages 309-320
  12. Walter Noordzij, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart, Bouke P. C. Hazenberg
    Pages 321-335
  13. Frank M. Bengel
    Pages 337-346
  14. Alexis Vrachimis, Michael Schäfers, Lars Stegger, Christian Wenning
    Pages 347-365
  15. Erick Alexanderson, Albert Flotats, Luis Eduardo Juárez-Orozco
    Pages 367-385
  16. Beata E. Chrapko, Casper F. M. Franssen
    Pages 387-404
  17. Giorgio Treglia, Antonella Stefanelli, Ignasi Carrio
    Pages 405-418
  18. Walter Noordzij, Andor W. J. M. Glaudemans, René A. Tio, Mike J. L. DeJongste, Hans C. Klein, Riemer H. J. A. Slart
    Pages 419-435
  19. L. P. Salm, B. F. Bulten, H. W. M. Van Laarhoven, L. F. De Geus-Oei
    Pages 437-451
  20. Back Matter
    Pages 453-465

About this book


This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed.

Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.


Clinical Application Myocardial Innervation PET-CT Radiopharmaceuticals SPECT-CT

Editors and affiliations

  • Riemer H.J.A. Slart
    • 1
  • René A. Tio
    • 2
  • Philip H. Elsinga
    • 3
  • Markus Schwaiger
    • 4
  1. 1.Nuclear Medicine and Molecular ImagingUniversity Medical Center GroningenGroningenThe Netherlands
  2. 2.Thorax center CardiologyUniversity Medical Center GroningenGroningenThe Netherlands
  3. 3.Nuclear Medicine and Molecular ImagingUniversity Medical Center GroningenGroningenThe Netherlands
  4. 4.Nuklearmedizinische KlinikKlinikum Rechts der Isar Technische Universität MünchenMünchenGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2015
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-662-45073-4
  • Online ISBN 978-3-662-45074-1
  • Buy this book on publisher's site