Protein Toxin Structure

  • Michael W. Parker

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Joseph E. Alouf
    Pages 1-4
  3. Ingrid R. Vetter, Michael W. Parker, Franc Pattus, Demetrius Tsernoglou
    Pages 5-23
  4. David Eisenberg, Charles E. Bell, Melanie J. Bennett, R. John Collier, Michael P. Schlunegger, Boyd A. Steere et al.
    Pages 25-47
  5. Michael W. Parker, J. Thomas Buckley, F. Gisou van der Goot, Demetrius Tsernoglou
    Pages 79-95
  6. Carlo Petosa, Robert C. Liddington
    Pages 97-121
  7. David L. Scott, Rong-Guang Zhang, Edwin M. Westbrook
    Pages 123-146
  8. Marie E. Fraser, Maia M. Chernaia, Yuri V. Kozlov, Michael N. G. James
    Pages 173-190
  9. Penelope E. Stein, Bart Hazes, Randy J. Read
    Pages 191-216
  10. Douglas H. Ohlendorf, David T. Mitchell, G. Sridhar Prasad, R. Radhakrishnan, Cathleen A. Earhart, Patrick M. Schlievert
    Pages 217-229
  11. S. Swaminathan, William Furey, Martin Sax
    Pages 231-251
  12. Jon D. Robertus, Arthur F. Monzingo
    Pages 253-270
  13. Dominique Housset, Juan C. Fontecilla-Camps
    Pages 271-290
  14. Fei Gu, Anis Khimani, Stan Rane, William H. Flurkey, Robert F. Bozarth, Thomas J. Smith
    Pages 291-303
  15. Back Matter
    Pages 305-309

About this book


Joseph E. Alouf "The empirical basis of objective science has thus nothing 'abso­ lute' about it. Science does not rest upon solid bedrock. The bold structure of its theories rises, as it were, above swamp. It is like a building erected on piles. The piles are driven down from above into the swamp, but not down to any natural or 'given' base; and if we stop driving the piles deeper, it is not because we have reached firm ground. We simply stop when we are satisfied that the piles are firm enough to carry the structure, at least for the time being. " -Karl Popper (The Logic of Scientific Discovery) hen I was invited to write this introductory chapter I was hon­ W ored and pleased to have the opportunity to briefly highlight some important issues relevant to structural aspects of bacterial protein tox­ ins. The present book attempts for the first time to provide into one volume a series of chapters prepared by invited experts on the struc­ ture of these fascinating macromolecules. A particular emphasis is placed on the molecular features of these highly active biomolecules in rela­ tion to their biological properties and mechanisms of action. The researchers in bacterial protein toxinology of my generation have had the privilege of witnessing over 40 years the tremen­ dous development of this field of biological sciences, particularly in the past decade.


Termination ion channels membrane membrane ion channels protein proteins

Authors and affiliations

  • Michael W. Parker
    • 1
  1. 1.The Ian Potter Foundation Protein Crystallography LaboratorySt. Vincent’s Institute of Medical ResearchMelbourneAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-22354-3
  • Online ISBN 978-3-662-22352-9
  • Series Print ISSN 1431-0414
  • Buy this book on publisher's site