Myocardial Preconditioning

  • Cherry L. Wainwright
  • James R. Parratt

Part of the Medical Intelligence Unit book series (MIU.LANDES)

Table of contents

  1. Front Matter
    Pages N2-XIII
  2. David García-Dorado, Marisol Ruiz-Meana, José A. Barrabés
    Pages 19-34
  3. Karin Przyklenk, Peter Whittaker, Michel Ovize, Robert A. Kloner
    Pages 79-96
  4. Ben C. G. Gho, Monique M. G. Koning, René L. J. Opstal, Eric van Klaarwater, Dirk J. Duncker, Pieter D. Verdouw
    Pages 97-113
  5. Lucia Piacentini, Nigel J. Pyne
    Pages 147-166
  6. Tanya Ravingerová
    Pages 167-184
  7. Michael V. Cohen, Yongge Liu, James M. Downey
    Pages 185-206
  8. Back Matter
    Pages 277-285

About this book


This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium - a phenomenon which is switched on by stress and termed myocardial preconditioning. This volume describes the main features and characteristics of preconditioning, with respect to the time-course of the protective effect of the phenomenon (first and second windows) and the different sequelae of myocardial ischaemia against which it protects, such as myocardial injury, arrhythmias and contractile dysfunction. The proposed mechanisms underlying the fascinating form of cardioprotection are discussed. Among these are the role of endogenous labile mediators, receptor-linked G proteins, ATP-sensitive potassium channels and protein kinase C activation.


activation potassium protein proteins receptor

Authors and affiliations

  • Cherry L. Wainwright
    • 1
  • James R. Parratt
    • 1
  1. 1.Department of Physiology and PharmacologyUniversity of Strathclyde, Royal CollegeGlasgowScotland

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-22208-9
  • Online ISBN 978-3-662-22206-5
  • Series Print ISSN 1080-3645
  • Buy this book on publisher's site