Local Immunosuppression of Organ Transplants

  • Scott A. Gruber

Part of the Medical Intelligence Unit book series (MIU.LANDES)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Background

    1. Front Matter
      Pages 1-1
    2. Scott A. Gruber, Shengguang Xiao, Stephen E. Hughes
      Pages 3-11
    3. Stephen E. Hughes, Sardha Perera, Scott A. Gruber
      Pages 13-16
    4. Stephen E. Hughes, Sardha Perera, Scott A. Gruber
      Pages 17-21
  3. Pump-Based Local Infusion in Rat Allograft Models

    1. Front Matter
      Pages 23-23
    2. Mou-er Wang, Stanislaw M. Stepkowski, Barry D. Kahan
      Pages 39-45
    3. Norio Yoshimura, Chol Joo Lee, Takahiro Oka
      Pages 59-68
  4. Pump-Based Local Infusion in Canine Allograft Models

    1. Front Matter
      Pages 79-79
    2. Saiho Ko, Yoshiyuki Nakajima, Hiroshige Nakano
      Pages 97-105
  5. Other Drug Targeting Systems for Achieving Local Immunosuppression

    1. Front Matter
      Pages 107-107
    2. Chris E. Freise, Nancy L. Ascher, John P. Roberts
      Pages 109-118
    3. Saiho Ko, Yoshiyuki Nakajima, Hiroshige Nakano
      Pages 119-129
    4. Gilbert J. Burckart, Robert J. Keenan, Aldo T. Iacono, Bartley P. Griffith
      Pages 131-139
    5. Kirby S. Black, Charles W. Hewitt
      Pages 141-152
    6. Ali R. Djalilian, Edward J. Holland
      Pages 153-159
    7. Steven F. Bolling, Vinod Labhasetwar, Robert J. Levy
      Pages 161-168
    8. Jonathan S. Bromberg, LiHui Qin
      Pages 169-180
    9. Ming Yu, A. Alfred Chahine, Christian Stoeckert, Henry T. Lau
      Pages 181-192
  6. Conclusion

    1. Scott A. Gruber
      Pages 211-211
  7. Back Matter
    Pages 213-217

About this book


For the first time a complete review of the research work done over the past 30 years by leading investigators around the world in targeting immunosuppressants to both solid-organ and cellular transplants is available in a single volume. One section consists of studies conducted in rat allograft models using osmotic minipumps for delivery of a variety of immunosuppressants. The book will be of great benefit to researchers in the fields of transplant immunology, pharmacology and drug delivery and targeting, particularly those involved in drug development.


drug drug delivery drug development immunology immunosuppression organ pharmacology research

Authors and affiliations

  • Scott A. Gruber
    • 1
  1. 1.Albany Medical CollegeAlbanyUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-22107-5
  • Online ISBN 978-3-662-22105-1
  • Series Print ISSN 1080-3645
  • Buy this book on publisher's site