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Glycoproteins and Human Disease

  • Inka Brockhausen
  • William Kuhns

Part of the Medical Intelligence Unit book series (MIU.LANDES)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Inka Brockhausen, William Kuhns
    Pages 1-1
  3. Inka Brockhausen, William Kuhns
    Pages 3-4
  4. Inka Brockhausen, William Kuhns
    Pages 13-31
  5. Inka Brockhausen, William Kuhns
    Pages 37-46
  6. Inka Brockhausen, William Kuhns
    Pages 47-49
  7. Inka Brockhausen, William Kuhns
    Pages 51-59
  8. Inka Brockhausen, William Kuhns
    Pages 61-75
  9. Inka Brockhausen, William Kuhns
    Pages 77-84
  10. Inka Brockhausen, William Kuhns
    Pages 99-107
  11. Inka Brockhausen, William Kuhns
    Pages 109-120
  12. Inka Brockhausen, William Kuhns
    Pages 121-126
  13. Inka Brockhausen, William Kuhns
    Pages 127-131
  14. Inka Brockhausen, William Kuhns
    Pages 133-139
  15. Inka Brockhausen, William Kuhns
    Pages 141-150
  16. Inka Brockhausen, William Kuhns
    Pages 151-155
  17. Inka Brockhausen, William Kuhns
    Pages 157-173
  18. Inka Brockhausen, William Kuhns
    Pages 175-193
  19. Inka Brockhausen, William Kuhns
    Pages 195-200
  20. Inka Brockhausen, William Kuhns
    Pages 201-206
  21. Inka Brockhausen, William Kuhns
    Pages 207-208
  22. Inka Brockhausen, William Kuhns
    Pages 209-215
  23. Inka Brockhausen, William Kuhns
    Pages 217-220
  24. Inka Brockhausen, William Kuhns
    Pages 221-226
  25. Inka Brockhausen, William Kuhns
    Pages 227-236
  26. Inka Brockhausen, William Kuhns
    Pages 237-238
  27. Back Matter
    Pages 239-242

About this book

Introduction

Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. The glycosylation abnormalities found in disease are the result of complex rearrangements of the oligosaccharide assembly by glycosyltransferases. This volume reviews several mechanisms that may underly the extremely complex alterations in disease. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically. Specific therapy may be aimed at correcting glycosylation abnormalities based on knowledge of the mechanisms leading to the disease phenotype and the three-dimensional interactions between carbohydrates and carbohydrate-binding molecules.

Keywords

Hydra cancer carbohydrate carbohydrates diseases inflammation leukemia metastasis molecule protein proteins therapy

Authors and affiliations

  • Inka Brockhausen
    • 1
  • William Kuhns
    • 1
  1. 1.Department of Biochemistry Research Institute, Hospital for Sick ChildrenUniversity of TorontoTorontoCanada

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-21960-7
  • Copyright Information Springer-Verlag Berlin Heidelberg 1997
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-21962-1
  • Online ISBN 978-3-662-21960-7
  • Series Print ISSN 1080-3645
  • Buy this book on publisher's site