Genetic Mechanisms in Multiple Endocrine Neoplasia Type 2

  • Barry D. Nelkin

Part of the Medical Intelligence Unit book series (MIU.LANDES)

Table of contents

  1. Front Matter
    Pages i-xi
  2. B. A. J. Ponder, M. A. Pierotti
    Pages 21-35
  3. Alfredo Fusco, Giancarlo Vecchio, Nina A. Dathan, Francesca Carlomagno, Pier Paolo Di Fiore, Massimo Santoro
    Pages 37-59
  4. Michael P. Myers, Kenneth D. Swanson, Gary Landreth
    Pages 61-98
  5. Arthur S. Tischler, Ronald A. DeLellis
    Pages 119-136
  6. Andrew F. Russo, Thomas M. Lanigan
    Pages 137-161
  7. Barry D. Nelkin
    Pages 163-182
  8. Barry D. Nelkin
    Pages 195-198
  9. Back Matter
    Pages 199-201

About this book


This book examines what is known about the molecular biology of multiple endocrine neoplasia, type 2 (MEN2). Mutations and alterations in gene expressions and signal transduction are placed in the context of their effects on the biology of the thyroid and adrenal cells which generate cancers in MEN2. Thus, this volume addresses the ret mutations, the effects these mutations may have on signal transduction, and developmental and neurobiological aspects of the cells affected of MEN2, and provides the basic researcher - in genetics, signal transduction, cell transformation, developmental or neurobiology - with a better understanding of how the knowledge generated by each of these fields intercalates within the overall biology of MEN2.


biology cell gene gene expression genetics molecular biology mutation

Authors and affiliations

  • Barry D. Nelkin
    • 1
  1. 1.Johns Hopkins Oncology Center, School of MedicineJohns Hopkins UniversityBaltimoreUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-21950-8
  • Online ISBN 978-3-662-21948-5
  • Series Print ISSN 1080-3645
  • Buy this book on publisher's site