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Cardiac Energetics

Basic Mechanisms and Clinical Implications

  • Editors
  • R. Jacob
  • Hj. Just
  • Ch. Holubarsch

Table of contents

  1. Front Matter
    Pages I-IX
  2. Cardiac energetics as related to basic mechanisms and mechanical conditions

  3. Cardiac energetics as related to ontogenesis, chronic myocardial transformation and inotropic interventions

    1. Front Matter
      Pages 119-119
    2. J. W. de Jong, P. W. Achterberg
      Pages 121-126
    3. M. Vogt, R. Jacob, K. Noma, B. Onegi, H. Rupp
      Pages 161-172
    4. S. Winegrad, G. McClellan, A. Weisberg, L. E. Lin, S. Weindling, R. Horowits
      Pages 183-189
    5. G. Kissling, H. Rupp, R. Jacob
      Pages 191-200
    6. N. Takeda, T. Ohkubo, T. Hatanaka, A. Takeda, I. Nakamura, M. Nagano
      Pages 215-221
    7. Z. El Alaoui-Talibi, J. Moravec
      Pages 223-231
    8. Gerd Hasenfuss, Ch. Holubarsch, H. Just, E. Blanchard, L. A. Mulieri, N. R. Alpert
      Pages 251-259
  4. Cardiac energetics in hypoxia and ischaemia

    1. Front Matter
      Pages 261-261
    2. E. van der Merwe, I. S. Harper, P. Owen, A. Lochner, S. Wynchank, L. H. Opie
      Pages 285-287
    3. E. Röth, B. Török, Zs. Pollák, Gy. Temes, G. Morvay
      Pages 335-345
    4. B. Török, E. Röth, B. Mezey, Gy. Temes, K. Tóth, Zs. Pollák
      Pages 347-353
  5. Cardiac energetics in human heart: Clinical implications

    1. Front Matter
      Pages 355-355
    2. Christian Holubarsch, G. Hasenfuss, H. W. Heiss, T. Meinertz, H. Just
      Pages 377-388
    3. B. E. Strauer
      Pages 389-402
    4. Gerd Hasenfuss, Ch. Holubarsch, W. H. Heiss, T. Bonzel, T. Meinertz, H. Just
      Pages 403-409
  6. Back Matter
    Pages 421-425

About these proceedings

Introduction

Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysiological (hypertrophy, hypoxia, ischaemia and heart failure) conditions. Moreover, cardiac energetics should be an important consideration in the choice and application of drugs especially in the case of vasodilators, inotropic agents and in cardioprotective measures. Only by considering energetics at the subcellular, cellular, and whole-heart level we can arrive at a better understanding of cardiac performance and ultimately better clinical judgement and drug therapy. Quantification of myocardial energetics will also help to determine the optimal time for surgical interventions such as valvular replacement or aneurysm resection. The present volume is the outcome of an international symposium on cardiac energetics held in Gargellen/Montafon (Austria), June 1986. The contributions will certainly help bridge the existing gap between basic research involving isolated structures and that involving the whole organ, on the one hand, and render the results derived from basic research applicable to clinical problems, on the other hand.

Keywords

aneurysm cardiac function drugs heart heart failure

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-11289-2
  • Copyright Information Steinkopff-Verlag Darmstadt 1987
  • Publisher Name Steinkopff, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-11291-5
  • Online ISBN 978-3-662-11289-2
  • Buy this book on publisher's site