Signaling Pathways for Translation

Stress, Calcium, and Rapamycin

  • Robert E. Rhoads

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 27)

Table of contents

  1. Front Matter
    Pages I-X
  2. Gert C. Scheper, Roel Van Wijk, Adri A. M. Thomas
    Pages 39-56
  3. Angus C. Nairn, Masayuki Matsushita, Kent Nastiuk, Atsuko Horiuchi, Ken-Ichi Mitsui, Yoshio Shimizu et al.
    Pages 91-129
  4. Anne-Claude Gingras, Brian Raught, Nahum Sonenberg
    Pages 143-174
  5. Back Matter
    Pages 175-176

About this book


This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.


Calcium Endoplasmatisches Reticulum Rapamycin Ribosomen Zelltod apoptosis cell cell death phosphorylation protein protein synthesis proteins regulation synthesis translation

Editors and affiliations

  • Robert E. Rhoads
    • 1
  1. 1.Department of Biochemistry and Molecular BiologyLouisiana State University Health Sciences CenterShreveportUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-07505-6
  • Online ISBN 978-3-662-09889-9
  • Series Print ISSN 0079-6484
  • Buy this book on publisher's site