Advertisement

Regulation of Alternative Splicing

  • Philippe Jeanteur

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 31)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. J. R. Sanford, D. Longman, J. F. Cáceres
    Pages 33-58
  3. P. Förch, J. Valcárcel
    Pages 127-151
  4. J. Y. Wu, H. Tang, N. Havlioglu
    Pages 153-185
  5. D. L. Black, P. J. Grabowski
    Pages 187-216
  6. Back Matter
    Pages 241-245

About this book

Introduction

The generality and quantitative extent of alternative splicing have only now begun to be fully appreciated. The first draft of the complete human genome led to the surprisingly low figure of about 32,000 genes. The extensive use of alternative splicing and its consequences in terms of coding capacity could account for this discrepancy and help fill the complexity gap between the genome and the proteome. After a computer-based assessment of the frequency of alternative splicing, this book addresses mechanistic aspects followed by examples of its involvement in important cellular processes. Finally, it raises the possibility of artificial modulation of alternative splicing by antisense nucleotides.

Keywords

Drosophila Nucleotide RNA RNA Splicing Termination biology cellular processes development gene expression genes genome genomics molecular biology protein regulation

Editors and affiliations

  • Philippe Jeanteur
    • 1
  1. 1.Institute of Molecular Genetics of MontpellierCNRSMontpellier Cedex 05France

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-09728-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-07858-3
  • Online ISBN 978-3-662-09728-1
  • Series Print ISSN 0079-6484
  • Buy this book on publisher's site