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Intracellular Antibodies

Development and Applications

  • Antonino Cattaneo
  • Silvia Biocca

Part of the Biotechnology Intelligence Unit book series (BIOIU)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Antonino Cattaneo, Silvia Biocca
    Pages 1-7
  3. Andrew Bradbury
    Pages 15-39
  4. Silvia Biocca, Antonino Cattaneo
    Pages 59-83
  5. Antonino Cattaneo, Patrizia Piccioli, Francesca Ruberti
    Pages 85-104
  6. Silvia Biocca, Antonino Cattaneo
    Pages 105-124
  7. Rosella Franconi, Paraskevi Tavladoraki, Eugenio Benvenuto
    Pages 145-171
  8. Nicola Gargano, Luisa Fasulo, Silvia Biocca, Antonino Cattaneo
    Pages 173-186
  9. Antonino Cattaneo, Silvia Biocca
    Pages 187-189
  10. Back Matter
    Pages 191-196

About this book

Introduction

Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.

Keywords

Antikörper Expression Genexpression Immunologie antibody biotechnology diseases gene gene expression gene therapy immunology infectious disease protein resistance virus

Editors and affiliations

  • Antonino Cattaneo
    • 1
  • Silvia Biocca
    • 2
  1. 1.Biophysics SectorInternational School for Advanced Studies (SISSA)TriesteItaly
  2. 2.Department of Experimental Medicine and Biochemical SciencesUniversity of Rome “Tor Vergata”RomaItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-07992-8
  • Copyright Information Springer-Verlag Berlin Heidelberg 1997
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-07994-2
  • Online ISBN 978-3-662-07992-8
  • Buy this book on publisher's site