Advertisement

Dendritic Cells and Virus Infection

  • Alexander Steinkasserer

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 276)

Table of contents

  1. Front Matter
    Pages I-X
  2. Interaction of Dendritic Cells and Viruses

    1. R. M. Steinman, A. Granelli-Piperno, M. Pope, C. Trumpfheller, R. Ignatius, G. Arrode et al.
      Pages 1-30
    2. T. B. H. Geijtenbeek, Y. van Kooyk
      Pages 31-54
    3. S. Schneider-Schaulies, I. M. Klagge, V. ter Meulen
      Pages 77-101
    4. C. Servet-Delprat, P.-O. Vidalain, H. Valentin, C. Rabourdin-Combe
      Pages 103-123
    5. N. Sevilla, S. Kunz, D. McGavern, M. B. A. Oldstone
      Pages 125-144
    6. D. Kobelt, M. Lechmann, A. Steinkasserer
      Pages 145-161
  3. Dendritic Cells and Immune-Intervention Strategies

    1. T. G. Berger, E. S. Schultz
      Pages 163-197
    2. R. Offringa, A. de Jong, R. E. M. Toes, S. H. van der Burg, C. J. M. Melief
      Pages 215-240
    3. J. Humrich, L. Jenne
      Pages 241-259
    4. M. Larsson, J. F. Fonteneau, N. Bhardwaj
      Pages 261-275
    5. G. Arrode, C. Davrinche
      Pages 277-294
  4. Back Matter
    Pages 295-298

About this book

Introduction

Dendritic cells (DC) are vital to induce potent anti-viral immune responses. However, viruses have developed a large number of different escape mechanisms in order to overcome the host immune system. A prime target in this respect are DC, since they are the only antigen presenting cell able to induce also naive T cells. In the present CTMI-volume the interaction between several viruses, including HIV-1, SIV, EBV, measles virus, LCMV and HSV-1, with DC will be described and discussed. It will become clear to the reader that DC often play a dual role during viral infections. On the one hand they are able to mount potent antiviral immune responses, and the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes were they infect their prime target cells. In the second part of this volume several DC specific immune intervention strategies will be presented. This includes topics such as DC vaccination strategies in immunotherapy, viral vectors for the genetic modification of DC and cross presentation of virus infected cells by DC.

Keywords

Antigen Epstein-Barr Virus HIV Herpes Simplex Virus-1 Immunodeficiency Virus cell cells dendritic cells immunodeficiency immunosuppression immunotherapy infection infections vaccination virus

Editors and affiliations

  • Alexander Steinkasserer
    • 1
  1. 1.Dermatologische KlinikUniversität ErlangenErlangenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-06508-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-07926-9
  • Online ISBN 978-3-662-06508-2
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site