• Marek Michalak

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Marek Michalak, Christi Andrin
    Pages 1-10
  3. Shairaz Baksh, Marek Michalak
    Pages 11-30
  4. Frank Parlati, Richard Hemming, Wei-Jia Ou, John J. M. Bergeron, David Y. Thomas
    Pages 43-57
  5. Karl-Heinz Krause
    Pages 59-76
  6. Chintamani D. Atreya, Gregory P. Pogue, Nishi K. Singh, Hira L. Nakhasi
    Pages 89-115
  7. Richard D. Sontheimer, Tho Q. Nguyen, Shih-Tsung Cheng, Tsu-San Lieu, J. Donald Capra
    Pages 117-139
  8. R. Chris Bleackley, Michael J. Pinkoski, Eric A. Atkinson
    Pages 141-153
  9. David J. Pinsky, Keisuke Kuwabara, Ann Marie Schmidt, Charles A. Lawson, Claude Benedict, Johan Broekman et al.
    Pages 155-168
  10. Deborah C. Jaworski, Glen R. Needham
    Pages 169-180
  11. Victor B. Hatcher, Christina Samathanam
    Pages 181-200
  12. Back Matter
    Pages 201-213

About this book


This book is about calreticulin, a multifunctional calcium binding protein first discovered over 20 years ago. The protein has been described in various locations: endoplasmic reticulum, nuclear envelope, cytoplasmic granules, nucleus, cell surface and even secreted into the blood stream. This volume outlines the newly discovered functions for calreticulin including its control of calcium homeostasis, modulation of steroid-sensitive gene expression, control of viral RNA replication, modulation of nuclear transport, role in T lymphocyte activation and cytotoxic killing, chaperone function, control of adhesion-dependent signaling via integrins, possible role in the biology of ticks, in the pathology of autoimmune diseases and in blood function.


Activation Calcium RNA autoimmune disease biology cell chaperone chaperones endoplasmic reticulum gene gene expression protein replication

Authors and affiliations

  • Marek Michalak
    • 1
  1. 1.MRC Group in Molecular Biology of Membranes, Department of BiochemistryUniversity of AlbertaEdmontonCanada

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-06205-0
  • Online ISBN 978-3-662-06203-6
  • Series Print ISSN 1431-0414
  • Buy this book on publisher's site