Advertisement

Interferon: The Dawn of Recombinant Protein Drugs

  • J. Lindenmann
  • W.-D. Schleuning
Conference proceedings

Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 5)

About these proceedings

Introduction

Forty years of Interferon I wish to dedicate this short introduction to the memory of Alick Isaacs (1921-1967), and to that of Sir Christopher Andrewes (1896-1988). Let us go back more than 40 years. In 1956 Isaacs was in charge of the Wodd Influenza Centre. Andrewes was head of the division of bac­ teriology and virology, and deputy director of the National Institute for Medical Research in London. When researchers are faced with a seemingly new phenomenon, ex­ planations are easy to come by. These explanations fall into two broad categories: the phenomenon in question is either due to something or to the lack of something. I apologize for the primitive way in which I ex­ press this, but I am going to give three examples, scattered over 100 years, of what I mean. First example: in 1880 the great French microbiologist Louis Pas­ teur was involved in work on chicken cholera. He was struck by the following observation: if a suitable chicken broth was inoculated with the bacterium, the organism grew profusely and the liquid became tur­ bid. If he now freed the fluid, by sedimentation or filtration, from the bulk of the organisms and re-inoculated it with the same bacterium, no growth occurred.

Keywords

Multiple Sclerosis Protein Drugs cancer cancer therapy cytokine cytokines interferon protein proteins

Editors and affiliations

  • J. Lindenmann
    • 2
  • W.-D. Schleuning
    • 1
  1. 1.Schering AGBerlinGermany
  2. 2.GockhausenSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-03787-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-03789-8
  • Online ISBN 978-3-662-03787-4
  • Series Print ISSN 0947-6075
  • Buy this book on publisher's site