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Drug Discovery and Evaluation

Pharmacological Assays

  • H. Gerhard Vogel
  • Wolfgang H. Vogel
Book

Table of contents

  1. Front Matter
    Pages I-XXXI
  2. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 1-149
  3. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 150-167
  4. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 168-182
  5. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 183-203
  6. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 204-316
  7. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 317-349
  8. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 350-359
  9. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 360-420
  10. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 421-460
  11. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 461-534
  12. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 535-597
  13. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 598-623
  14. H. Gerhard Vogel, Wolfgang H. Vogel
    Pages 624-725
  15. Andreas W. Herling, Jochen Maas, Karl Seeger
    Pages 726-740
  16. Back Matter
    Pages 741-759

About this book

Introduction

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research.
An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.

Keywords

drug drug discovery drugs endocrinology pharmacological tests pharmacology research toxicology

Editors and affiliations

  • H. Gerhard Vogel
    • 1
    • 2
  • Wolfgang H. Vogel
    • 3
  1. 1.Johann Wolfgang Goethe Universität FrankfurtFrankfurt am MainGermany
  2. 2.Philipps Universität MarburgMarburgGermany
  3. 3.Department of Pharmacology Jefferson Medical CollegeThomas Jefferson UniversityPhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-03333-3
  • Copyright Information Springer-Verlag Berlin Heidelberg 1997
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-03335-7
  • Online ISBN 978-3-662-03333-3
  • Buy this book on publisher's site