Solvent Extraction in Biotechnology

Recovery of Primary and Secondary Metabolites

  • Karl Schügerl

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Karl Schügerl
    Pages 1-1
  3. Karl Schügerl
    Pages 2-51
  4. Karl Schügerl
    Pages 52-65
  5. Karl Schügerl
    Pages 66-197
  6. Back Matter
    Pages 198-216

About this book


Solvent Extraction in Biotechnology deals with the reco- very and purification of primary and secondary metabolites by solvent extraction. In the first part the reaction engineering principles: definitions, thermodynamic fundamentals, and system models, the kinetics of mass transfer between two phases without and with chemical reaction as well as extraction equipment, which are important for downstream processing in biotechnology, are considered in detail. The special part of the book describes the recovery of low-molecular metabolites: alcohols, acids and antibiotics with organic solvents, carrier-modifier-solvent systems, supercritical gases as well as with liquid membrane techniques. Several practical examples are given for the recovery of different metabolites as well as for the calculation of the extraction processes necessary for equipment design. Besides solvent extraction, novel separation techniques with liquid membrane, microemulsion and reversed micelles are also presented. This book will introduce the biochemical engineer and process engineer to the recovery of products from complex cultivation broths by modern techniques of solvent extraction and help them with process design.


Biochemie Biochemistry Biotechnologie Downstream Processing Seperation Techniques Trennverfahren biotechnology

Authors and affiliations

  • Karl Schügerl
    • 1
  1. 1.Institut für Technische ChemieUniversity of HannoverHannoverGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1994
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-08190-3
  • Online ISBN 978-3-662-03064-6
  • Buy this book on publisher's site