Biological Effects of Polynucleotides

Proceedings of the Symposium on Molecular Biology, Held in New York, June 4–5, 1970 Sponsored by Miles Laboratories, Inc.

  • Roland F. BeersJr.
  • Werner Braun
Conference proceedings

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Template Effects and Their Modification

    1. Front Matter
      Pages 1-1
  3. Interferon Stimulation

    1. Front Matter
      Pages 25-25
    2. Maurice R. Hilleman, George P. Lampson, Alfred A. Tytell, A. Kirk Field, Marjorie M. Nemes, Irwin H. Krakoff et al.
      Pages 27-44
    3. Samuel Baron, Herman DuBuy, Charles E. Buckler, Martin Johnson, Michael Worthington
      Pages 45-54
    4. H. B. Levy, R. Adamson, P. Carbone, V. DeVita, A. Gazdar, J. Rhim et al.
      Pages 55-65
    5. Thomas C. Merigan, Erik De Clercq, Fritz Eckstein, Robert D. Wells
      Pages 67-78
    6. Clarence Colby, Michael J. Chamberlin, Peter H. Duesberg, Melvin I. Simon
      Pages 79-87
    7. L. D. Hamilton
      Pages 107-128
  4. Stimulation of Antibody Formation and Cell-Mediated Immunity

  5. Pharmacological Aspects of Polynucleotide Effects

    1. Front Matter
      Pages 247-247
    2. Warren R. Stinebring, Marlene Absher
      Pages 249-257
    3. Frederick S. Philips, Martin Fleisher, L. D. Hamilton, Morton K. Schwartz, Stephen S. Sternberg
      Pages 259-273
  6. Polynucleotide-Associated Events in Immunocompetent Cells

  7. Back Matter
    Pages 339-344

About these proceedings


In recent years our horizons regarding the role of nucleic acids in biological systems have been expanded vastly by the finding that these molecules not only carry and transmit specific infOImation but also can act as less specific triggers of antiviral factors and of immunological responses. The latter properties are of particular interest in terms of possible utilization in human and veterinary medicine and consequently led, in the last few years, to the development of a new research area that combines both fundamental and applied problems in a uniquely attractive way. Furthermore, the importance and the complexity of the problems has attracted investigators from many fields, including molecular biologists, virologists, immunologists, chemists, biophysicists, oncologists, pharmacologists, and clinicians. A discussion of new developments in this area of biological effects of polynucleotides, with particular emphasis on interferon induction and modification of immune responses, therefore, seemed a logical topic for one of the annual symposia that Miles Laboratories, Inc. , has sponsored in recent years. The manage­ ment of Miles accepted the suggestion with enthusiasm and thus once again earned the gratitude of the scientific community for sponsoring a catalytic meeting that was principally concerned with basic research problems and only tangentially with immediate applications. Springer-Verlag agreed to publish the proceedings of the meeting which was held at the Americana Hotel in New York City, June 4-5, 1970 and attracted an unusually large audience.


Nucleotide RNA base cell immune response immunity lymphocytes nucleic acid peptides pharmacology protein synthesis

Editors and affiliations

  • Roland F. BeersJr.
    • 1
  • Werner Braun
    • 2
  1. 1.Johns Hopkins UniversityBaltimoreUSA
  2. 2.Rutgers UniversityNew BrunswickUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1971
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-85774-4
  • Online ISBN 978-3-642-85772-0
  • Buy this book on publisher's site