Diagnosis of Human Viruses by Polymerase Chain Reaction Technology

  • Yechiel Becker
  • Gholamreza Darai

Part of the Frontiers of Virology book series (FRVIROLOGY, volume 1)

Table of contents

  1. Front Matter
    Pages I-XVII
  2. Human Retroviruses

  3. Human Hepatitis Viruses

    1. Front Matter
      Pages 55-55
    2. Geoffrey Dusheiko, Jianye Xu, Arie J. Zuckermann
      Pages 67-85
    3. Amy J. Weiner, Venkatakrishna Shyamala, J. Eric Hall, Michael Houghton, Jang Han
      Pages 86-100
    4. Anna Linda Zignego, Paul Deny, Paolo Gentilini, Christian Brechot
      Pages 101-116
  4. Human Herpes Viruses

    1. Front Matter
      Pages 117-117
    2. R. H. Boerman, A. C. B. Peters, E. P. J. Arnoldus, A. K. Raap, A. M. van Loon, B. R. Bloem et al.
      Pages 119-133
    3. Ravi Mahalingam, Randall Cohrs, Aud N. Dueland, Donald H. Gilden
      Pages 134-146
    4. Mark F. Mangano, Richard L. Hodinka, Jordan G. Spivack
      Pages 147-156
    5. Hans Knecht, Roland Sahli, David J. L. Joske, Edith Bachmann, Fedor Bachmann, Daniel Hayoz et al.
      Pages 157-170
    6. K. Kondo, C. Tomomori, T. Kondo, T. Mukai, T. Yamamoto, K. Yamanishi
      Pages 171-181
  5. Human Papova Viruses

  6. Airborne and Respiratory Viruses

    1. Front Matter
      Pages 229-229
    2. Linda Ho, George Terry
      Pages 231-240
    3. Augustine Rajakumar, Michelle Inkster, Ian D. Manger, Ella M. Swierkosz, Irene T Schulze
      Pages 260-271
    4. Tim Skern, Heinrich Kovar, Gunhild Jug, Herbert Auer, Helge Torgensen, Klaus Hartmuth et al.
      Pages 272-284
    5. Annika Allard, Göran Wadell
      Pages 297-315
    6. Janet N. Stewart, Samir Mounir, Pierre J. Talbot
      Pages 316-327
  7. Disease Causing RNA Viruses

    1. Front Matter
      Pages 329-329
    2. Steven Tracy, Nora M. Chapman, Jeanne M. Pistillo
      Pages 331-344
    3. Ralf Stohwasser, Lutz B. Giebel, Karl Raab, E. K. F. Bautz, Gholamreza Darai
      Pages 372-388
    4. N. Tordo, H. Bourhy, D. Sacramento
      Pages 389-405
  8. Summary

  9. Back Matter
    Pages 415-426

About this book


The basis for the effective treatment and cure of a patient is the rapid diagnosis of the disease and its causative agent, which is based on the analysis of the clinical symptoms coupled with laboratory tests. Although rapid advance­ ments have been made in the laboratory diagnosis of virus diseases, the neces­ sary isolation of the causative virus from the clinical specimens is a relatively long procedure. Viruses which integrate into the cellular DNA (such as human immunodeficiency virus, HIV -1, or hepatitis B virus) are difficult to identify by molecular techniques, while viruses which exist in the clinical material in low concentrations are even more formidable to identify. Recently, the application of the polymerase chain reaction (peR) technique developed by K. D. Mullis and detailed in the study by Saiki et al. (1985) led to a revolution in virus diagnosis. The peR technique was rapidly applied to the diagnosis of viruses in clinical material. Volume 1 of Frontiers of Virology provides new information on the advan­ tages of the use of the peR for the diagnosis of many human disease-causing viruses, as well as on some problems with its use.


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Editors and affiliations

  • Yechiel Becker
    • 1
  • Gholamreza Darai
    • 2
  1. 1.Department of Molecular Virology Faculty of MedicineHebrew University of JerusalemJerusalemIsrael
  2. 2.Institut für Medizinische Virologieder Universität HeidelbergHeidelbergGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1992
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-84768-4
  • Online ISBN 978-3-642-84766-0
  • Series Print ISSN 1431-357X
  • Buy this book on publisher's site