Adult Respiratory Distress Syndrome

An Aspect of Multiple Organ Failure Results of a Prospective Clinical Study

  • J. A. Sturm

Table of contents

  1. Front Matter
    Pages I-IX
  2. Introduction

    1. J. A. Sturm
      Pages 1-4
  3. Clinical Aspects

    1. Front Matter
      Pages 5-5
    2. H.-C. Pape, C.-J. Kant
      Pages 7-10
    3. A. Seekamp, U. Obertacke, J. A. Sturm
      Pages 11-16
    4. U. Obertacke, Th. Joka, M. Reuter, K. P. Schmit-Neuerburg
      Pages 17-21
    5. Th. Joka, J. A. Sturm, U. Obertacke, G. Regel
      Pages 22-24
    6. U. Obertacke, Th. Joka, C. Neumann
      Pages 25-29
    7. C. Neumann, J. A. Sturm, G. Regel
      Pages 30-33
    8. Th. Joka, U. Obertacke, J. A. Sturm, M. L. Nerlich
      Pages 34-44
    9. M. L. Nerlich
      Pages 45-56
  4. Activation of Humeral Cascade Systems

  5. Activation of Cellular Systems

    1. Front Matter
      Pages 89-89
    2. A. Dwenger, G. Regel, G. Schweitzer, G. Röllig, J. Lindena
      Pages 91-127
    3. Th. Joka, U. Obertacke, J. Bruch, M. Reuter, K. P. Schmit-Neuerburg
      Pages 128-134
    4. J. Seidel, J. Mirkhani, M. Behrmann, W. Stangel
      Pages 135-155
    5. G. Regel, K. F. Gratz, T. Pohlemann, J. A. Sturm, H. Tscherne
      Pages 156-167
  6. Activation of Inflammatory Cells

  7. Endothelial and Epithelial Mechanisms of Injury

    1. Front Matter
      Pages 213-213
    2. J. A. Sturm, D. H. Wisner, H.-J. Oestern, C.-J. Kant, H. Tscherne, H.-C. Pape et al.
      Pages 230-244
    3. W. Seeger, U. Pison, Th. Joka, H. Neuhof
      Pages 245-256
    4. E. Kreuzfelder, U. Obertacke, B. Neumann, O. Thraenhart
      Pages 257-264
  8. Experimental Studies

  9. Back Matter
    Pages 341-347

About this book


l. A. STURM In modern society, trauma remains the number one cause of death in people under 50 years, but, despite this, very little attention has been paid to trauma care compared with other diseases such as malignancy or myocardial infarction (Table 1). The efforts that have been made in medical care, however, have showed some success; for example although the frequency of traffic accidents in the Federal Republic of Germany has remained constant over the years, the number of deaths resulting from them has decreased (Fig. 1). The results of improvements in rescue systems, surgical techniques, and intensive care are evident, as shown by a review of the statistics of about 3000 multiple trauma patients treated in the last 15 years at the trauma de­ partment of Hannover Medical School which reflects the progress that has been made in medical care. After the problem posed by posttraumatic kidney failure had been solved in the 1960s and 1970s, the adult respiratory distress syndrome (ARDS) became the biggest problem in the 1970s and 1980s (Fig. 2). ARDS as a single entity disappeared in the literature in the early 1980s and was replaced by the so-called multiple organ failure (MOF) syndrome. Between 1985 and 1990 35% of the patients in our intensive care unit developed MOF, and 70% of them died. Overall MOF mortality has remained constant since 1985 at about 20% (Fig. 3).


(ARDS), Veränderungen in den Zellverbänden (ARDS), changes in the immun system Adult Respiratory Syndrome (ARDS), cell system changes Atmen Immunsystem Lungenversagen Polytrauma Trauma bacteria blood multiple organ failure pathogenesis pathophysiology physiology proteins

Editors and affiliations

  • J. A. Sturm
    • 1
  1. 1.Department of Trauma SurgeryHannover Medical SchoolHannover 61Germany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1991
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-52180-8
  • Online ISBN 978-3-642-84098-2
  • Buy this book on publisher's site