HLA in Narcolepsy

  • Yutaka Honda
  • Takeo Juji

Table of contents

  1. Front Matter
    Pages I-XII
  2. Y. Honda
    Pages 1-9
  3. T. Juji
    Pages 10-23
  4. K. Matsuki, Y. Honda, M. Satake, T. Juji
    Pages 58-75
  5. C. B. Lock, K. I. Welsh, J. D. Parkes, A. So, D. C. Briggs, R. W. Vaughan et al.
    Pages 76-88
  6. M. Billiard, J. Seignalet, H. Betuel, A. Marcadet, L. Gebuhrel, A. C. Freidel et al.
    Pages 89-96
  7. J. Montplaisir, G. Poirier
    Pages 97-107
  8. C. Guilleminault, J. Holloman, C. Grumet, T. Kilduff, H. O. McDevitt, W. C. Dement et al.
    Pages 108-113
  9. K. Meier-Ewert, G. Mueller-Eckhardt, D. J. Schendel
    Pages 114-120
  10. T. Naohara, Y. Honda, T. Juji
    Pages 121-129
  11. K. Tokunaga, K. Matsuki, T. Juji, Y. Honda
    Pages 130-136
  12. H. Inoko
    Pages 137-149
  13. K. Matsuki, T. Juji, Y. Honda
    Pages 150-157
  14. J. D. Parkes, K. Welsh, N. Langdon, C. Lock
    Pages 158-171
  15. A. Asaka, K. Matsuki, M. Uchikawa, T. Juji, Y. Honda
    Pages 191-201
  16. Back Matter
    Pages 203-208

About this book


The Second International Symposium on Narcolepsy was held at Fairchild Auditorium, Stanford University, on 6-7 July 1985 under the presidency of Drs. William C. Dement and Christian Guillemi­ nault. It succeeded the First International Symposium on Narco­ lepsy held in La Grande Motte, France, organized by Pierre Pas­ souant in July 1975 in commemoration of the 100th anniversary of the publication of Jean B. E. Gelineau's paper which proposed the naming of narcolepsy. At the second narcolepsy symposium, many important research reports on both basic and clinical aspects of narcolepsy were given by investigators from many countries of the world. Audience inter­ est was particularly attracted by the section on the relationship be­ tween HLA and narcolepsy, in which recent evidence that almost all narcoleptic patients are HLA-DR2 positive was reported by in­ vestigators from Japan, England, France, Canada, and the United States. The close relationship between the HLA antigens, hitherto considered as immune-related genetic markers encoded by genes on human chromosome 6, and narcolepsy appeared to open a new approach not only for the research of narcolepsy but also for the mechanism of sleep in general. Publication of all these new findings on the association of HLA and narcolepsy was considered; an outline was worked out and all the groups agreed to prepare a contribution covering the various aspects of this topic.


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Editors and affiliations

  • Yutaka Honda
    • 1
  • Takeo Juji
    • 2
  1. 1.Neuropsychiatric Research InstituteSeiwa HospitalShinjuku-ku, TokyoJapan
  2. 2.Blood Transfusion ServiceTokyo University HospitalBunkyo-ku, TokyoJapan

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1988
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-83389-2
  • Online ISBN 978-3-642-83387-8
  • Buy this book on publisher's site