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The Conduct of a Cooperative Clinical Trial

  • Kenneth Stanley
  • Jan Stjernswärd
  • Mary Isley

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 77)

Table of contents

  1. Front Matter
    Pages I-XI
  2. Kenneth Stanley, Jan Stjernswärd, Mary Isley
    Pages 1-3
  3. Kenneth Stanley, Jan Stjernswärd, Mary Isley
    Pages 4-7
  4. Kenneth Stanley, Jan Stjernswärd, Mary Isley
    Pages 8-12
  5. Kenneth Stanley, Jan Stjernswärd, Mary Isley
    Pages 13-17
  6. Kenneth Stanley, Jan Stjernswärd, Mary Isley
    Pages 18-24
  7. Back Matter
    Pages 25-78

About this book

Introduction

The purpose of this monograph is to address the basic mecha­ nisms for organizing trials. Is is meant to serve as a guide to individuals planning to form a cooperative group as well as to cooperative groups who wish to revise and refine their existing procedures. Current literature deals with many components of conducting clinical trials, such as trial design considerations, randomization, and methods of analysis. But there is a lack of accessible knowledge concerning data flow, data processing, and group organization which causes difficulty for many multi­ institutional cooperative trials. Multi-institutional cooperative studies require greater atten­ tion to detail than studies within a single institution. For single institution studies, a single protocol document may be suffi­ cient. In a cooperative group, however, it is necessary to standardize various aspects where little variation may be pre­ sent in a single institution study. Patients must be entered in a uniform fashion, data collection and evaluation should be standardized, and there must be a mechanism to insure the timely collection of essential data.

Keywords

Kontrollierte Therapiestudie Krebs clinical trial data processing evaluation

Authors and affiliations

  • Kenneth Stanley
    • 1
  • Jan Stjernswärd
    • 2
  • Mary Isley
    • 3
  1. 1.Division of BiostatisticsSidney Farber Cancer InstituteBostonUSA
  2. 2.Cancer UnitWorld Health Organization (WHO)GenevaSwitzerland
  3. 3.Frontier Science and Technology Research Foundation, Inc.AmherstUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-81630-7
  • Copyright Information Springer-Verlag Berlin Heidelberg 1981
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-81632-1
  • Online ISBN 978-3-642-81630-7
  • Series Print ISSN 0080-0015
  • Buy this book on publisher's site