The Cytochemical Bioassay of Polypeptide Hormones

  • Joseph Chayen

Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 17)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Joseph Chayen
    Pages 1-11
  3. Joseph Chayen
    Pages 12-19
  4. Joseph Chayen
    Pages 20-42
  5. Joseph Chayen
    Pages 43-51
  6. Joseph Chayen
    Pages 52-68
  7. Joseph Chayen
    Pages 69-79
  8. Joseph Chayen
    Pages 94-99
  9. Joseph Chayen
    Pages 106-129
  10. Joseph Chayen
    Pages 130-139
  11. Joseph Chayen
    Pages 140-155
  12. Joseph Chayen
    Pages 156-165
  13. Back Matter
    Pages 175-210

About this book


The cytochemical bioassay system was described in a short abstract in 1971, and more fully, in the cytochemical bioassay of corticotrophin, in 1972. Since then, cytochemical bioassays have been described for several polypeptide hormones, and these assays are already widely used. It is expedient that the subject should be reviewed, as it is in this monograph, by one writer who has had the good fortune to have taken part in the growth of cytochemistry from its early origins to its present position as the basis of possibly the most sensitive bioassay system currently available. However, it should be noted that major contributions have been made by many, both to the development of the subject and to the establishment of the bioassays. The object of this preface is to try to give some perspective to the growth of this subject and to record that the cytochemical bioassay system has been fostered by many outstanding scientists in an atmosphere of remarkable goodwill. To begin with, there could have been no cytochemical bioassays until cytochem­ istry had been converted from its rather unsure origins into a precise and quantitative form of cellular biochemistry. This was done with skill and enthusiastic dedication by my colleagues, Dr. Lucille Bitensky, Dr. F. P. Altman, Dr. R. G. L. W. Poulter and Mr. A. A. Silcox, first at the Royal College of Butcher, Dr.


ACTH NADPH Polypeptide biochemistry blood cell development enzymes growth hormone hormones hypothalamus metabolism physiology thyroid hormone tissue

Authors and affiliations

  • Joseph Chayen
    • 1
  1. 1.Division of Cellular BiologyThe Mathilda and Terence Kennedy Institute of RheumatologyLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1980
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-81461-7
  • Online ISBN 978-3-642-81459-4
  • Series Print ISSN 0077-1015
  • Buy this book on publisher's site