Major Sex-Determining Genes

  • Susumu Ohno

Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 11)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. Sexual Dimorphism as a Dispensable Appendage of the Sex-Determining Mechanism

    1. Front Matter
      Pages 1-1
    2. Susumu Ohno
      Pages 3-6
    3. Susumu Ohno
      Pages 7-10
  3. H-Y Antigen and Chromosomal Determination of Primary (Gonadal) Sex

  4. Nuclear-Cytosol Androgen-Receptor Protein and Hormonal Secondary (Extragonadal) Sex Determination

  5. Back Matter
    Pages 129-142

About this book


Upon wresting the control of the earth from the Titans, Zeus assigned the task of creating living creatures to two Titan brothers who had sided with him in the epic battle just concluded. Because Epimetheus, who had been endowed only with hindsight, had the first hand in this creation, all the good attributes were exhaus­ ted by the time the lion, the elephant and other animals were created. When the time came for the creation of man, there were precious few materials left to work with. Not surprisingly, man was made weak and naked. Prometheus took pity on this miscreation and gave man the use of fire. For this foresight, Zeus meted out horrible punishment, binding Prometheus to a rocky pillar in the Caucasas Moun­ tains and letting a vulture consume his liver daily. It seems to me that the ancient Greeks in their unfathomable wisdom under­ stood the essence of the evolutionary process very well. Had Escherichia coli of 200 million years or so ago been endowed with the foresight to anticipate the eventual emergence of and subsequent dominance by mammals of this Earth, they would no doubt have equipped themselves, in anticipation of the coming cer­ tainty, with the lac operon to deal with lactose in the suckling mammalian infant's gut. Had they been able to do so, the actual emergance of mammals would have exerted no selective pressure upon existing E. COLI.


animals genes sex

Authors and affiliations

  • Susumu Ohno
    • 1
  1. 1.Department of Biology, City of HopeNational Medical CenterUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1979
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-81263-7
  • Online ISBN 978-3-642-81261-3
  • Series Print ISSN 0077-1015
  • Buy this book on publisher's site