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© 1976

The Immune System

  • Fritz Melchers
  • Klaus Rajewsky
Conference proceedings

Part of the Colloquium der Gesellschaft für Biologische Chemie book series (MOSBACH, volume 27)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Antibody Structure

    1. Front Matter
      Pages 1-1
    2. R. J. Poljak, L. M. Amzel, B. L. Chen, Y. Y. Chiu, R. P. Phizackerley, F. Saul et al.
      Pages 19-25
    3. R. Huber, J. Deisenhofer, P. M. Colman, M. Matsushima, W. Palm
      Pages 26-40
  3. Antibody Structural Genes

    1. Front Matter
      Pages 55-55
    2. R. R. Porter
      Pages 57-64
    3. K. Eichmann, C. Berek, G. Hämmerling, S. Black, K. Rajewsky
      Pages 65-74
    4. C. Milstein, G. G. Brownlee, C. C. Cheng, P. H. Hamlyn, N. J. Proudfoot, T. H. Rabbitts
      Pages 75-85
    5. S. Tonegawa, N. Hozumi
      Pages 86-97
  4. Immunocompetent Cells

    1. Front Matter
      Pages 99-99
    2. L. Du Pasquier
      Pages 101-115
    3. H. Wigzell
      Pages 131-140
    4. H. Fischer
      Pages 173-177
  5. The Major Histocompatibility Complex and Cellular Recognition

    1. Front Matter
      Pages 179-179

About these proceedings

Introduction

The cells of the immune system generate a large variety of binding sites which differ in their binding specificities and can therefore react specifically with a large variety of ligands. These binding sites are part of receptor molecules, enabling the system to react to the universe of antigens. The classical antigen receptor is the antibody molecule, and accord­ ingly the first session of this colloquium deals with a classical sub­ ject, namely antibody structure. Dramatic recent advances in this field make it possible to interrelate primary and three-dimensional struc­ ture both to each other and to function, i.e. the binding of antigen and possible reactions occurring in the antibody molecule upon antigen binding. The latter point is of particular interest since it may be relevant not only for effector functions of antibodies such as the binding of complement, but also for the triggering of a lymphocyte through its antibody receptor for antigen.

Keywords

Antibody Antigen Immune System Immunologie Lymphocytes

Editors and affiliations

  • Fritz Melchers
    • 1
  • Klaus Rajewsky
    • 2
  1. 1.Basel Institute of ImmunologyBaselSwitzerland
  2. 2.Institut für GenetikKölnGermany

Bibliographic information

  • Book Title The Immune System
  • Editors F. Melchers
    K. Rajewsky
  • Series Title Colloquium der Gesellschaft für Biologische Chemie
  • DOI https://doi.org/10.1007/978-3-642-81083-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1976
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-07976-7
  • Softcover ISBN 978-3-642-81085-5
  • eBook ISBN 978-3-642-81083-1
  • Series ISSN 0366-5887
  • Edition Number 1
  • Number of Pages XIV, 302
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cell Biology
    Pharmacy
    Molecular Medicine
    Allergology
    Immunology
  • Buy this book on publisher's site