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Bacterial Infection: Close Encounters at the Host Pathogen Interface

  • Peter K. Vogt
  • Michael J. Mahan

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 225)

Table of contents

  1. Front Matter
    Pages I-IX
  2. C. P. Conner, D. M. Heithoff, M. J. Mahan
    Pages 1-12
  3. H. A. Shuman, M. Purcell, G. Segal, L. Hales, L. A. Wiater
    Pages 99-112
  4. T. A. Mietzner, S. B. Tencza, P. Adhikari, K. G. Vaughan, A. J. Nowalk
    Pages 113-135
  5. S. E. F. D’Orazio, C. M. Collins
    Pages 137-164
  6. Back Matter
    Pages 165-173

About this book

Introduction

When it comes to bacterial disease, we are living in a state of false security. Antibiotics have indeed brought unprecedented health benefits, protection from and cure of bacterial diseases during the past 50 years. But there are ominous signs that the fortress and the defenses built on antibiotics are crumbling. They are crum­ bling because we wittingly or unwittingly created selective con­ ditions for the emergence of superior pathogens that can no longer be controlled by antibiotics. There are numerous warnings. After a long period of eclipse tuberculosis has now emerged as a serious threat unchecked by antibiotic treatment. Recent years have seen reports of cholera epidemics, of anthrax infections, of serious problems with Salmonella and even with E. coli, just to name a few. Mankind is in a race with microbial invaders. The challenge is to anticipate and respond to developments that affect the precarious balance between man and microbe. This will re­ quire new knowledge and it will take time for an effective appli­ cation of that knowledge.

Keywords

antibiotic antibiotics antigen bacteria bacterial infection gene gene expression genetics infection infections microbe pathogenesis regulation toxin virology

Editors and affiliations

  • Peter K. Vogt
    • 1
  • Michael J. Mahan
    • 2
  1. 1.Division of Oncovirology, BCC 239, Department of Molecular and Experimental MedicineThe Scripps Research InstituteLa JollaUSA
  2. 2.Department of Molecular, Cellular, and Developmental BiologyUniversity of CaliforniaSanta BarbaraUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-80451-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-80453-3
  • Online ISBN 978-3-642-80451-9
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site