Role of Nitric Oxide in Sepsis and ADRS

  • M. P. Fink
  • Didier Payen

Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 24)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Biochemistry of Nitric Oxide and Regulation of Gene Expression

    1. Front Matter
      Pages 1-1
    2. L. L. Shears, T. R. Billiar
      Pages 14-28
    3. J. Wilkinson, S. Sriskandan, J. Cohen
      Pages 62-69
  3. Effects of Nitric Oxide on Various Cell Types and Organs

    1. Front Matter
      Pages 71-71
    2. A. Kumar, J. E. Parrillo
      Pages 73-99
    3. J. R. Kirsch, R. J. Traystman
      Pages 125-137
    4. R. L. Danner, J. Cobb, A. L. Van Dervort
      Pages 155-180
    5. M. P. Fink, N. Unno, A. L. Salzman
      Pages 181-198
  4. Nitric Oxide in Shock

    1. Front Matter
      Pages 199-199
    2. G. A. Fonseca, R. G. Kilbourn
      Pages 232-252
    3. J. L. Vincent, J. G. Preiser, H. Zhang
      Pages 253-273
  5. Nitric Oxide and the Lung

    1. Front Matter
      Pages 281-281
    2. M. J. D. Griffiths, T. W. Evans
      Pages 283-297
    3. L. E. Gustafsson, P. A. Lönnqvist, M. G. Persson
      Pages 298-307
  6. Nitric Oxide Inhalation in RDS and ARDS

    1. Front Matter
      Pages 321-321
    2. W. M. Zapol, W. E. Hurford
      Pages 323-341
    3. C. G. Frostell
      Pages 342-354
    4. J. C. Mercier, A. T. Dinh-Xuan, S. H. Abman
      Pages 355-379
    5. D. M. Payen, R. Kong, C. Gatecel
      Pages 380-398
    6. H. Gerlach, R. Rossaint, K. J. Falke
      Pages 399-413
    7. A. T. Dinh-Xuan, F. Brunet, J. F. Dhainaut
      Pages 414-425
  7. Back Matter
    Pages 427-430

About this book


Nitric Oxide (NO) is a free radical, a gas, and a pluripotent product of mammalian cells. Only a few years ago, scientific discussions of NO were largely held in the context of the chemistry of air pollution. Now, however, the great significance of NO as a signalling and cytotoxic molecule has captererd the attention of the biomedical community.
This book provides a very up-to-date review of the role of NO in sepsis and ARDS. Consideration is given to NO both as a pathophysiologic mediator as well as a therapeutic agent. An internationally recognized group of scientists and clinicians have contributed chapters dealing with cutting-edge science and practical clinical strategies. Numerous tables and charts have been included to aid the reader in understanding this fascinating and important subject.


ARDS Arginin Edotoxin Lipopolysaccharid Sepsis air pollution arginine attention cells cerebral ischemia hypoxia lipopolysaccharide molecule respiratory failure shock

Editors and affiliations

  • M. P. Fink
    • 1
  • Didier Payen
    • 2
  1. 1.Department of SurgeryBeth Israel HospitalBostonUSA
  2. 2.Department of Anesthesiology and Intensive CareLariboisière University HospitalParis Cedex 10France

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-79922-8
  • Online ISBN 978-3-642-79920-4
  • Series Print ISSN 0933-6788
  • Buy this book on publisher's site