Signalling Mechanisms — from Transcription Factors to Oxidative Stress

  • Lester Packer
  • Karel W. A. Wirtz
Conference proceedings

Part of the NATO ASI Series book series (volume 92)

Table of contents

  1. Front Matter
    Pages I-X
  2. Components of Signal Transduction

    1. Jacopo Meldolesi, Fabio Grohovaz
      Pages 1-10
    2. Adrian A. A. Spillmann, Christine E. Bandtlow, Flavio Keller, Martin E. Schwab
      Pages 23-28
    3. Shun-ichi Nakamura, Kouji Ogita, Yasutomi Nishizuka, Yoshinori Asaoka, Françoise Hullin
      Pages 29-47
    4. Valérie Planat, Jean-Marc Lanau, Michel Record, Hugues Chap
      Pages 49-55
    5. Ian N. Fleming, Stephen J. Yeaman
      Pages 57-64
    6. Linda Pooley, Miles D. Houslay
      Pages 65-76
    7. Annie Otto-Bruc, Bruno Antonny, Marc Chabre, Pierre Chardin, Eva Faurobert, T. Minh Vuong
      Pages 77-85
    8. Zafiroula Georgoussi, Graeme Milligan, Christine Zioudrou
      Pages 87-98
    9. Carlos B. Duarte, Ana L. Carvalho, Arsélio P. Carvalho
      Pages 115-124
    10. Guy Vergères, Stéphane Manenti, Thomas Weber
      Pages 125-137
    11. Theodore G. Sotiroudis, George A. Maridakis, Anna-Maria G. Psarra, Athanassios E. Evangelopoulos
      Pages 139-156
  3. Antioxidants, Oxidative Stress and Hypoxia

  4. Transcription Factors and Gene Induction

    1. Per-Erik Strömstedt, Jan Carlstedt-Duke, Jan-Åke Gustafsson
      Pages 305-364
    2. Trausti Baldursson, Connie Gram, Jens Knudsen, Karsten Kristiansen, Susanne Mandrup
      Pages 365-374
    3. Guy Haegeman, Walter Fiers
      Pages 375-382
    4. Margriet J. B. M. Vervoordeldonk, Casper G. Schalkwijk, Rosa M. Sanchez, Josef Pfeilschifter, Henk van den Bosch
      Pages 383-393
    5. Roel Schaapveld, Jan Schepens, Frank Oerlemans, Michel Streuli, Bé Wieringa, Wiljan Hendriks
      Pages 407-419
  5. Various Functions of Membrane Lipids

  6. Addendum

    1. Sandra Marmiroli, Alberto Bavelloni, Irene Faenza, Rashmi Sood, Spartaco Santi, Stefania Cecchi et al.
      Pages 443-443
    2. Sandra Marmiroli, Alberto Bavelloni, Irene Faenza, Rashmi Sood, Spartaco Santi, Stefania Cecchi et al.
      Pages 445-452
  7. Back Matter
    Pages 453-462

About these proceedings


A NATO Advanced Study Institute on "Molecular Mechanisms of Transcellular Signaling: from the Membrane to the Gene" was held on the Island of Spetsai, Greece, from August 15- 27, 1994. The aim of this Institute was to bring together researchers in the field of signal transduction mechanisms, transcription factors and gene regulation with those actively involved in studies on the implications of oxygen radicals and antioxidant defence mechanisms for cell function. As diverse as these fields may be, the emergence of their interconnection during the course of the Institute was an eye-opener for students and lecturers alike. 2 Presentations and discussions focussed on the role of Ca +, G-proteins, protein kinase C and phospholipases in signaling mechanisms. These broad principles were extended to transcription factors and gene regulation with an emphasis on the steroid hormone receptor superfamily and NFKB. Basic principles of free radical formation and antioxidant action (vitamin E and C) were presented and discussed in connection with effects on signaling pathways. This book present the content of the major lectures and a selection of the most relevant posters. These proceedings offer a comprehensive account of the most important topics discussed at the Institute. The book is intended to make the proceedings accessible to a large audience.


Calcium Signalübertragung Transkriptionsfaktoren antioxidant cell cell nucleus cells defense mechanism gen regulation gene oxidative stress protein signal transduction transcription transcription factors

Editors and affiliations

  • Lester Packer
    • 1
  • Karel W. A. Wirtz
    • 2
  1. 1.Department of Molecular and Cell BiologyUniversity of CaliforniaBerkeleyUSA
  2. 2.Centre for Biomembranes and Lipid EnzymologyUtrecht UniversityUtrechtThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-79677-7
  • Online ISBN 978-3-642-79675-3
  • Buy this book on publisher's site