Systemic Lupus Erythematosus

  • Peter A. Miescher

Table of contents

  1. Front Matter
    Pages I-VI
  2. Peter A. Miescher
    Pages 1-2
  3. Shozo Izui, Ramón Merino, Masahiro Iwamoto, Liliane Fossati
    Pages 3-22
  4. Barry S. Handwerger, Violeta Rus, Ludmila da Silva, Charles S. Via
    Pages 23-50
  5. John B. Winfield, Philip Fernsten, Jan Czyzyk, Ena Wang, John Marchalonis
    Pages 71-80
  6. E. Nigel Harris, Silvia S. Pierangeli
    Pages 93-115
  7. Michael D. Lockshin
    Pages 117-129
  8. Alan M. Rosenberg
    Pages 131-149
  9. Peter A. Miescher, Hervé Favre, Robert Lemoine, You-Peng Huang
    Pages 165-181
  10. G. Valesini, R. Priori, A. Francia, G. Balestrieri, A. Tincani, P. Airo et al.
    Pages 183-191
  11. John M. Esdaile
    Pages 207-225

About this book


During the past 50 years, systemic lupus erythematosus (SLE) has been the main subject in the field of immunopathology. Each individual discovery was followed by the discovery of a multitude of related immune phenomena. This book reflects the present status of our understanding of this protean disease. Various animal models clearly show that different gene combinations can lead to the final clinical expression of SLE, with HLA class II genes probably responsible for the targeting of the autoimmune response. Similarly, research on cytokines in SLE patients has shown that SLE is a syndrome depending on different pathways. Finally, the question of prognosis is discussed. Fortunately, with every passing decade, the prognosis for patients with SLE gets better and better.


Erythematosus antibody antigen cytokine cytokines gene genes immune response lead necrosis pathogenesis pathology patients research systemic lupus erythematosus

Editors and affiliations

  • Peter A. Miescher
    • 1
  1. 1.Division d’Hématologie, Centre de Transfusion SanguineHôpital Cantonal UniversitaireGeneva 4Switzerland

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-79624-1
  • Online ISBN 978-3-642-79622-7
  • Buy this book on publisher's site