Prognostic Factors in Cancer

  • P. Hermanek
  • Mary K. Gospodarowicz
  • D. E. Henson
  • R. V. P. Hutter
  • L. H. Sobin

Table of contents

  1. Front Matter
    Pages I-XVI
  2. M. K. Gospodarowicz, P. Hermanek, D. E. Henson
    Pages 1-11
  3. E. W. Strong, H. Kasdorf, J. M. Henk
    Pages 12-22
  4. C. Calearo, A. Pastore
    Pages 23-27
  5. A. Antonaci, J. Brierley, G. Bacchi, F. Consorti, C. Consoli, A. Manzini et al.
    Pages 28-36
  6. J. D. Roder, H. J. Stein, J. R. Siewert
    Pages 37-46
  7. P. Hermanek, K. Maruyama, L. H. Sobin
    Pages 47-63
  8. P. Hermanek, L. H. Sobin
    Pages 64-79
  9. B. J. Cummings
    Pages 80-87
  10. C. Wittekind
    Pages 88-93
  11. M. T. Carriaga, D. E. Henson
    Pages 94-99
  12. M. T. Carriaga, D. E. Henson
    Pages 100-104
  13. M. Yamamoto, Y. Saitoh, P. Hermanek
    Pages 105-117
  14. H. Asamura, T. Naruke
    Pages 118-129
  15. H. Fukuma
    Pages 130-137
  16. S. Toma, W. Hohenberger, R. Palumbo, O. Schmidt, G. Nicolò, G. Canavese et al.
    Pages 138-148
  17. P. Hermanek, H. Breuninger
    Pages 149-151
  18. P. Hermanek, N. N. Blinov
    Pages 152-164
  19. H. B. Burke, R. V. P. Hutter, D. E. Henson
    Pages 165-176
  20. J. L. Benedet, D. M. Miller, E. Kovacs, H. Ludwig
    Pages 177-184
  21. A. Fyles, P. Kirkbride
    Pages 185-192
  22. J. L. Benedet, T. G. Ehlen, E. Kovacs, H. Ludwig
    Pages 193-202
  23. A. C. Rosen, M. J. Klein
    Pages 203-206
  24. A. Pfleiderer
    Pages 207-215
  25. L. J. Denis, P. A. Catton, M. K. Gospodarowicz, G. P. Murphy, P. O. Hedlund, F. K. Mostofi
    Pages 216-223
  26. M. K. Gospodarowicz, J. F. G. Sturgeon
    Pages 224-233
  27. M. K. Gospodarowicz, J. E. Montie
    Pages 234-240
  28. M. K. Gospodarowicz
    Pages 241-248
  29. G. K. Lang, C. W. Spraul, G. O. H. Naumann
    Pages 249-256
  30. K. Nomura, A. B. M. F. Karim
    Pages 257-262
  31. M. K. Gospodarowicz, L. Specht, S. B. Sutcliffe
    Pages 263-270
  32. M. K. Gospodarowicz, M. Hayat
    Pages 271-280
  33. Back Matter
    Pages 281-290

About this book


M. K. Gospodarowicz, P. Hermanek, and D. E. Henson Attention to innovations in cancer treatment has tended to eclipse the importance of prognostic assessment. However, the recognition that prognostic factors often have a greater impact on outcome than available therapies and the proliferation of biochemical, molecular, and genetic markers have resulted in renewed interest in this field. The outcome in patients with cancer is determined by a combination of numerous factors. Presently, the most widely recognized are the extent of disease, histologic type of tumor, and treatment. It has been known for some time that additional factors also influence outcome. These include histologic grade, lymphatic or vascular invasion, mitotic index, performance status, symptoms, and most recently genetic and biochemical markers. It is the aim of this volume to compile those prognostic factors that have emerged as important determinants of outcome for tumors at various sites. This compilation represents the first phase of a more extensive process to integrate all prognostic factors in cancer to further enhance the prediction of outcome following treatment. Certain issues surround­ ing the assessment and reporting of prognostic factors are also considered. Importance of Prognostic Factors Prognostic factors in cancer often have an immense influence on outcome, while treatment often has a much weaker effect. For example, the influence of the presence of lymph node involvement on survival of patients with metastatic breast cancer is much greater than the effect of adjuvant treatment with tamoxifen in the same group of patients [5].


Krebs Prognose Prognostische Faktoren Staging TNM TNM staging system cancer carcinoma classification prognosis prognostic factors tumor classification

Editors and affiliations

  • P. Hermanek
    • 1
  • Mary K. Gospodarowicz
    • 2
  • D. E. Henson
    • 3
  • R. V. P. Hutter
    • 4
    • 5
  • L. H. Sobin
    • 6
    • 7
  1. 1.Chirurgische Universitätsklinik ErlangenErlangenGermany
  2. 2.Princess Margaret Hospital, Department of Radiation OncologyUniversity of TorontoTorontoCanada
  3. 3.Early Detection Branch, Division of Cancer Prevention and ControlNational Cancer InstituteBethesdaUSA
  4. 4.University of Medicine and DentistryNew Jersey Medical SchoolNewarkUSA
  5. 5.Department of PathologySaint Barnabas Medical CenterLivingstonUSA
  6. 6.Uniformed Services University of the Health SciencesBethesdaUSA
  7. 7.Division of Gastrointestinal PathologyArmed Forces Institute of PathologyUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-58688-3
  • Online ISBN 978-3-642-79395-0
  • Buy this book on publisher's site