Chromosomal Alterations

Origin and Significance

  • Günter Obe
  • Adayapalam T. Natarajan

Table of contents

  1. Front Matter
    Pages I-XI
  2. L. H. F. Mullenders, R. J. Sakkers, H. H. Kampinga, A. W. T. Konings
    Pages 21-30
  3. W. Traut, H. Winking, C. Plass, D. Weichenhan, B. Kunze, T. Hellwig et al.
    Pages 31-41
  4. A. T. Natarajan, S. Vermeulen, M. Grigorova, J. J. W. A. Boei, E. T. Sakamoto Hojo, H. J. Oh et al.
    Pages 50-56
  5. J. S. King, J. W. Phillips, W. F. Morgan
    Pages 64-75
  6. J. R. K. Savage, A. N. Harvey
    Pages 76-91
  7. F. Palitti, P. Mosesso, D. Dichiara, A. Schinoppi, M. Fiore, L. Bassi
    Pages 103-115
  8. P. Finnon, D. C. Lloyd, A. A. Edwards
    Pages 192-202
  9. C. Streffer, W.-U. Müller, K. Wuttke
    Pages 214-222
  10. M. A. Hultén, A. S. H. Goldman
    Pages 235-251
  11. G. Obe, L. Riedel, W.-D. Heller, E. Sennewald, G. Scherer, F. Adlkofer
    Pages 307-318
  12. H. Fender, U. Wolf, F. Gensicke, G. Wolf, D. Arndt
    Pages 319-332
  13. B. A. Reed, C. K. Lee, B. G. Brown, C. R. E. Coggins, A. W. Hayes, D. J. Doolittle
    Pages 362-379
  14. I. Schubert, R. Rieger
    Pages 380-394
  15. Back Matter
    Pages 395-402

About this book


Due to sensitive molecular biological techniques, our understanding of chromosomal aberrations is steadily increasing. Provided here is a review of basic and applied aspects of the field. Chromosome structure, induction of DNA lesions by different clastogenic agents and their repair, induction of aberrations by agents which affect specific sequences in the DNA, and factors affecting induction and yield of chromosomal aberrations are covered.
Further, topics such as automation of aberration scoring, problems associated with using chromosomal aberrations and micronuclei in population monitoring and the importance of chromosomal aberration assays in mutagenicity testing of chemicals are included.


Chromosom Chromosomal Aberrations Chromosomen Chromosomenaberrationen DNA Zytogenetik chromosome cytogenetics genetics mutagen mutagenicity mutation

Editors and affiliations

  • Günter Obe
    • 1
  • Adayapalam T. Natarajan
    • 2
  1. 1.Department of GeneticsUniversity of EssenEssenGermany
  2. 2.Department of Radiation Genetics and Chemical MutagenesisState University of LeidenLeidenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1994
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-78889-5
  • Online ISBN 978-3-642-78887-1
  • Buy this book on publisher's site