Noninvasive Methods for the Quantification of Skin Functions

An Update on Methodology and Clinical Applications

  • Peter J. Frosch
  • Albert M. Kligman

Table of contents

  1. Front Matter
    Pages I-XIV
  2. The Basics: Methodology

    1. Front Matter
      Pages 1-1
    2. J. L. Leveque, P. Corcuff
      Pages 3-24
    3. U. Hoppe, R. Lunderstadt, G. Sauermann
      Pages 25-41
    4. R. A. Tupker, J. Pinnagoda, P.-J. Coenraads, J. P. Nater
      Pages 56-70
    5. D. Lubach, G. Neumann, M. Kietzmann
      Pages 71-82
    6. G. E. Piérard, C. Piérard-Franchimont
      Pages 83-91
    7. C. Queille-Roussel, L. Duteil, J. Czernielewski, H. Schaefer
      Pages 92-103
    8. S. el-Gammal, T. Auer, K. Hoffmann, U. Matthes, R. Hammentgen, P. Altmeyer et al.
      Pages 104-129
  3. Clinical Applications

    1. Front Matter
      Pages 131-131
    2. S. el-Gammal, K. Hoffmann, P. Steiert, J. Gassmüller, P. Altmeyer
      Pages 133-144
    3. H. G. Vogel
      Pages 145-180
    4. K. P. Wilhelm, A. B. Cua, H. I. Maibach
      Pages 190-203
    5. P. J. Frosch, A. Kurte, B. Pilz
      Pages 214-222
    6. L. Duteil, C. Queille-Roussel, J. Czernielewski
      Pages 223-240
    7. G. Sauermann, A. Herpens, U. Hoppe, A. Kligman
      Pages 252-271
    8. V. Wienert, A. Lentner, U. Böhler
      Pages 291-308
  4. Back Matter
    Pages 317-319

About this book


More than 10 years ago, I had the chance to visit the university hospital in Munster, Germany. At the outpatient clinic there, I accidently met a young dermatologist who was devoted to the study of the quantification of irritated skin during his busy daily clinical work. I sensed immediately that this Dr. P. Frosch was conducting his research with the ideals and enthusiasm which were so familiar to me. Soon we found that we shared a similar past experience; we both had begun our careers in dermatological investigation with the same mentor. For me it was more than 25 years ago that I first met Dr. Kligman, Professor at the University of Pennsylvania in Philadelphia, USA. I reminisced that I had been greatly shocked by his initial question ''As a dermatologist, do you want to study living or dead skin?" because, at that time and even today, whenever we cannot collect enough information about the skin with the naked eye, it is invasively removed is common practice to histologically examine a skin sample that from living tissue. Many dermatologists still would never think of studying the living intact skin itself noninvasively with the aid of existing advanced technologies to assess its structural and functional properties. At that time Dr. Kligman intended to build up a system of evaluating the skin from various aspects, using methods that had been unduly neglected in the past and introducing various technological instruments.


Acne Arterial and Venous Diseases Dermatopharmacology Eczema Skin Functions Ultrasound aging dermatology lipide pharmacology psoriasis skin

Editors and affiliations

  • Peter J. Frosch
    • 1
  • Albert M. Kligman
    • 2
  1. 1.Hautklinik der Städtischen Kliniken Dortmund Lehrstuhl DermatologieUniversität Witten/HerdeckeDortmund 1Germany
  2. 2.Department of DermatologyUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1993
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-78159-9
  • Online ISBN 978-3-642-78157-5
  • Buy this book on publisher's site