• Albert Herz
  • Huda Akil
  • Eric J. Simon

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 104 / 1)

Table of contents

  1. Front Matter
    Pages I-XXXVII
  2. Opioid Receptor/Multiplicity

    1. Front Matter
      Pages 1-1
    2. J. A. M. Smith, F. M. Leslie
      Pages 53-78
    3. R. S. Zukin, D. E. Pellegrini-Giampietro, C. M. Knapp, A. Tempel
      Pages 107-123
    4. R. B. Rothman, J. W. Holaday, F. Porreca
      Pages 217-237
  3. Chemistry of Opioids with Alkaloid Structure

    1. Front Matter
      Pages 239-239
    2. S. Archer
      Pages 241-277
    3. P. S. Portoghese
      Pages 279-293
    4. S. Spector, J. Donnerer
      Pages 295-304
  4. Opioid Peptides

    1. Front Matter
      Pages 305-305
    2. J. L. Roberts, N. Levin, D. Lorang, J. R. Lundblad, S. Dermer, M. Blum
      Pages 347-377
    3. N. Kley, J. P. Loeffler
      Pages 379-392
    4. R. Day, K. A. Trujillo, H. Akil
      Pages 449-470
    5. H. Khachaturian, M. K. H. Schaefer, M. E. Lewis
      Pages 471-497
    6. H. Teschemacher
      Pages 499-528
    7. L. D. Fricker
      Pages 529-545
    8. A. D. Corbett, S. J. Paterson, H. W. Kosterlitz
      Pages 645-679
    9. J. E. Pintar, R. E. M. Scott
      Pages 711-727
  5. Neurophysiology

    1. Front Matter
      Pages 729-729
    2. A. W. Duggan, S. M. Fleetwood-Walker
      Pages 731-771
    3. R. A. North
      Pages 773-797
  6. Back Matter
    Pages 799-815

About this book


In 1957 Otto SCHAUMANN, one of the pionieers in pharmacological research on morphine and the first to prepare synthetic opiates, presented a mono­ graph entitled "Morphin und morphiniihnliche Verbindungen" as Volume 12 of the Handbook of Experimental Pharmacology. Now, 35 years later, we are publishing in the same series a new comprehensive volume covering the present status of opioid research. Since that time the topic has expanded enormously. The identification of opioid receptors and the detection of their endogenous ligands were landmarks which opened a new era in opioid research and fertilized the entire field of neurobiology. The rapid develop­ ment of this field is illustrated in the figure, which represents the number of papers published on opioid research since 1970 (searches performed on the MEDLINE data base). 3000 Vl


Biochemie Biochemistry Opiat Opioid Peptides Opioider Opioids Pharmacology Pharmakologie base endogenous ligand neurobiology opioid

Editors and affiliations

  • Albert Herz
    • 1
  • Huda Akil
    • 2
  • Eric J. Simon
    • 3
  1. 1.Abteilung NeuropharmakologieMax-Planck-Institut für PsychiatrieMartinsriedGermany
  2. 2.Mental Health Research Institute, School of MedicineUniversity of MichiganAnn ArborUSA
  3. 3.Medical Center, School of MedicineNew York UniversityNew YorkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1993
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-77462-1
  • Online ISBN 978-3-642-77460-7
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site