Maturation Phenomenon in Cerebral Ischemia

Proceedings of the Satellite Symposium of the XIth International Congress of Neuropathology Tokyo, September 11–12, 1990

  • Umeo Ito
  • T. Kirino
  • T. Kuroiwa
  • Igor Klatzo
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-XVI
  2. U. Ito, T. Yamaguchi, H. Tomita, O. Tone, T. Shishido, H. Hayashi et al.
    Pages 1-13
  3. P. Bonnekoh, U. Oschlies, K.-A. Hossmann
    Pages 33-39
  4. F. Joó, J. Ikeda, J. Lohr, G. Nagashima, G. Mies, T. S. Nowak Jr. et al.
    Pages 41-47
  5. A. Tamura, T. Kirino, W. Fujie, M. Nakane, A. Teraoka, Y. Tahira et al.
    Pages 57-64
  6. M. J. Mossakowski, I. B. Zelman
    Pages 65-74
  7. K. Kawai, N. Saito, S. Xu, F. Joó, T. S. Nowak Jr., C. Ruetzler et al.
    Pages 75-86
  8. N. H. Diemer, M. B. Jørgensen, M. B. Jensen, T. Bruhn, E. Valente, F. F. Johansen
    Pages 95-105
  9. T. Wieloch, K. Bergstedt, M. Cardell, I. Gustafson, T. Honoré, B. R. Hu et al.
    Pages 107-119
  10. T. S. Nowak Jr., O. C. Osborne, J. Ikeda
    Pages 121-128
  11. G. Mies, K. Kawai, N. Saito, G. Nagashima, T. Nowak Jr., F. Joó et al.
    Pages 129-138
  12. K. Yamada, E. Kohmura, A. Kinoshita, J. Taguchi, T. Sakaguchi, K. Tsuruzono et al.
    Pages 139-149
  13. M. Spatz, K. Kumami, Y. Ueki, B. D. Djuricic, B. B. Mrsulja
    Pages 169-177
  14. R. Cahn, M. G. Borzeix, J. Angignard, S. Weber, J. Cahn
    Pages 179-184
  15. I. Klatzo, U. Ito
    Pages 195-199
  16. Back Matter
    Pages 201-208

About these proceedings


It has been well recognized that following an ischemic insult many nerve cells of the brain are not killed outright, but may suffer a "delayed neuronal death" or even recover. This led to the concept of "maturation phenomenon" with its main implication that the maturation of ischemic lesions may provide a "window of opportunity" i.e. a period of time when the injury to neuronal elements is still reversible, and during which an application of proper therapeutic measures might be successful. The symposium on Maturation Phenomenon in Cerebral Ischemia was the first international meeting focussed primarily on this subject and the resulting publication contains presentations and discussionsby prominent researchers engaged in this field. This book should stimulate further research on potential of brain tissue for recovery, and particularly with regard to a functional recovery of neurons suffering from chronic ischemic injury.


cerebral ischemia forebrain maturation phenomenon neuronal death neurons stroke

Editors and affiliations

  • Umeo Ito
    • 1
  • T. Kirino
    • 2
  • T. Kuroiwa
    • 3
  • Igor Klatzo
    • 4
  1. 1.Department of NeurosurgeryMusashino Red-Cross HospitalMusashino-shi, Tokyo 180Japan
  2. 2.Department of Neurosurgery, School of MedicineTeikyo UniversityItabashi-ku, TokyoJapan
  3. 3.Department of Neuropathology, Medical Research Center, School of MedicineTokyo Medical and Dental UniversityBunkyo-ku, Tokyo 113Japan
  4. 4.Laboratory of Neuropathology and Neuroanatomical SciencesNational Institute of HealthBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1992
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-54871-3
  • Online ISBN 978-3-642-77134-7
  • Buy this book on publisher's site