Pathology of the Nucleus

  • James C. E. Underwood

Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 82)

Table of contents

  1. Front Matter
    Pages I-IX
  2. J. C. E. Underwood
    Pages 1-15
  3. H. M. H. Kamel, J. Kirk, P. G. Toner
    Pages 17-89
  4. J. Crocker
    Pages 91-149
  5. T. J. Stephenson
    Pages 151-213
  6. P. Dal Cin, A. A. Sandberg
    Pages 257-288
  7. G. Terenghi, R. A. Fallon
    Pages 289-337
  8. Back Matter
    Pages 339-346

About this book


New techniques make it possible for investigators to examine and sometimes quantify various aspects of nuclear morphology and function; now they can derive clinically and biologically useful information about the nucleus. This book draws together a series of techniques which have been successfully applied to the study of the nucleus of tumour cells. These are of fundamental importance to researchers in tumour histopathology and medical oncology. Detailed reviews are given of various aspects of the morphology, ploidy and karyotypic status and function of the nuclei in the cells of tumours and preneoplastic lesions. Topics covered include nuclear morphology in tumour diagnosis, the ultrastructure of the nucleus, karyotypic analyses of solid tumours, flow cytometric assessment of nuclear ploidy and other parameters, histomorphometry of the nucleus, and in situ hybridisation.


DNA Grading Histopathologie Onkologie Pathologie Zellbiologie cell cell biology flow cytometry histopathology morphology oncology pathology tumor tumors

Editors and affiliations

  • James C. E. Underwood
    • 1
  1. 1.Department of PathologyUniversity of Sheffield Medical SchoolSheffieldUK

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-74670-3
  • Online ISBN 978-3-642-74668-0
  • Series Print ISSN 0070-2188
  • Buy this book on publisher's site