Modern Trends in Human Leukemia VIII

New Results in Clinical and Biological Research Including Pediatric Oncology

  • Rolf Neth
  • Robert C. Gallo
  • Melvyn F. Greaves
  • Gerhard Gaedicke
  • Sven Gohla
  • Klaus Mannweiler
  • Jörg Ritter

Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 32)

Table of contents

  1. Front Matter
    Pages I-LVII
  2. Frederick Stohlmann Jr. Memorial Lecture

  3. Clinical Aspects

    1. Front Matter
      Pages 23-23
    2. F. Lampert
      Pages 25-26
    3. W.-D. Ludwig, H. Seibt-Jung, J. V. Teichmann, B. Komischke, A. Gatzke, G. Gassner et al.
      Pages 51-57
    4. G. K. Rivera, D. K. Kalwinsky, J. Rodman, L. Kun, J. Mirro, Ching-Hon Pui et al.
      Pages 58-64
    5. J. Bogusławska-Jaworska, B. Kazanowska, B. Rodziewicz-Magott, W. Pietras, J. Armata, P. Daszkiewicz et al.
      Pages 71-74
    6. A. Petrakova, J. Stary, O. Hrodek, P. Goetz, K. Venclikova, J. Srajer
      Pages 75-77
    7. K. Swencz-Szczepanik, M. Krämer, L. Konopka, M. Brodzki, S. Pawelski, A. Deptala
      Pages 78-81
    8. J. Mirro Jr., W. R. Crom, D. K. Kalwinsky, V. M. Santana, D. K. Baker, J. Belt
      Pages 82-87
    9. Huang Meng-er, Ye Yu-chen, Chen Shu-rong, Chai Jin-ren, Lu Jia-xiang, Zhao Lin et al.
      Pages 88-96
    10. F. E. Cotter, P. A. Hall, B. D. Young, T. A. Lister
      Pages 97-100
    11. J. Hołowiecki, D. Lutz, V. Callea, M. Brugiatelli, S. Krzemień, B. Stella-Hołowiecka et al.
      Pages 104-108

About these proceedings

Introduction

You see things, and sa)' why? But I dream 1hings that never were, and I say, 11'hy 110t? George Bernhard Shaw Far ahead of his time, June 1st, 1909, Alexander Maximov communicated in a lecture, given in the Charite in Berlin, the fundamental knowledge, that there exists a lymphoid hemopoetic stem cell. Alexander Friedenstein explained that during the following years, Maximov also showed that the idea of interaction between hemopoetic cells and their stroma to be one of the most significant experiences. Monoclonal antibodies, recombinant DNA technics and the improvement of tissue culture models are the major developments to improve our possibilities to clarify growth and differentiation functions of hemopoetic cells. During the last two decades it was shown that soluble products, released from T cells, were not only involved in inducing B cells to produce specific immunoglobulin secretion after antigen stimulation. Furthermore, lymphokines together with other cytokines regulate the growth and differentiation of hemopoetic cells. As I have learned from Dick Gershon, our knowledge of the cellular basis for immunoregulation has come a long way since 450 B.C. Thucydides comments on the possible role of immune response in controlling the Black Death. Dick Gershon speculated that no scientific interest for these interesting observations was put forth at that time. Perhaps the problems, the Athenians were having with the Spartans, converted money from basis research into the military budget.

Keywords

Antigen Carcinom Evolution Interferon Knochenmarkstransplantation Leukämie Molekulargenetik Transplantation Virologie classification

Editors and affiliations

  • Rolf Neth
    • 1
  • Robert C. Gallo
    • 2
  • Melvyn F. Greaves
    • 3
  • Gerhard Gaedicke
    • 4
    • 5
  • Sven Gohla
    • 6
  • Klaus Mannweiler
    • 7
  • Jörg Ritter
    • 8
  1. 1.Medizinische Klinik, Abteilung für klinische ChemieUniversitäts-Krankenhaus EppendorfGermany
  2. 2.Laboratory of Tumor Cell BiologyNational Cancer InstituteBethesdaUSA
  3. 3.Chester Beatty LaboratoriesLeukemia Research Fund Centre, Institute of Cancer ResearchLondonUK
  4. 4.Abteilung Pädiatrie IIUniversitätskinderklinik und Poliklinik UlmUlmGermany
  5. 5.Universität UlmUlmGermany
  6. 6.Labor für Hautimmunologie, Bioverträglichkeit-Immunologie, Paul-Gerson-Unna-ForschungszentrumBeiersdorf-AGGermany
  7. 7.Heinrich-Pette-Institut für Experimentelle Virologie und ImmunologieGermany
  8. 8.Abteilung Hämatologie und OnkologieKinderklinik und Poliklinik der Westfälischen Wilhelms-UniversitätMünsterGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-74621-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-50967-7
  • Online ISBN 978-3-642-74621-5
  • Series Print ISSN 0440-0607
  • About this book