Biological Monitoring of Exposure and the Response at the Subcellular Level to Toxic Substances

Proceedings of the European Society of Toxicology Meeting held in Munich, September 4–7, 1988

  • Philip L. Chambers
  • Claire M. Chambers
  • Helmut Greim
Conference proceedings

Part of the Archives of Toxicology book series (TOXICOLOGY, volume 13)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. Young Scientists Award Lecture 1988

  3. Mechanism of Metal Carcinogenicity

    1. Front Matter
      Pages 19-19
    2. S. De Flora, D. Serra, C. Basso, P. Zanacchi
      Pages 28-39
    3. F. W. Sunderman Jr.
      Pages 40-47
    4. Th. Wolf, R. Kasemann, H. Ottenwälder
      Pages 48-51
  4. Individual Biomonitoring of Chemical Exposure

    1. Front Matter
      Pages 53-53
    2. R. A. Baan, A. M. J. Fichtinger-Schepman, L. Roza, G. P. van der Schans
      Pages 66-82
    3. P. B. Farmer, E. Bailey
      Pages 83-90
    4. K. Savela, S. Leppälä, K. Hemminki
      Pages 101-103
    5. G. Johanson, I. Michel, D. Norbäck, G. Nise, A. Tillberg
      Pages 108-111
    6. C. T. A. Evelo, J. Atema, J. H. J. Copius-Peereboom, P. H. S. Fijneman, J. C. L. M. Pertijs, R. P. Bos
      Pages 112-116
    7. K. Savolainen, P. Kurttio, T. Vartiainen, J. Kangas
      Pages 120-123
    8. H. Peter, S. Deutschmann, A. Muelle, B. Gansewendt, M. Bolt, E. Hallier
      Pages 128-132
  5. Genes for Drug Metabolizing Enzymes

    1. Front Matter
      Pages 139-139
    2. Y. Fujii-Kuriyama, A. Fujisawa-Sehara, K. Sogawa
      Pages 141-144
    3. T. Friedberg, C. Timms, W. Kissel, F. Oesch
      Pages 145-152
  6. Expression of Drug Metabolizing Enzymes in Eucaryotic Cells

    1. Front Matter
      Pages 153-153
    2. M. R. Waterman, J. I. Mason, M. X. Zuber, M. C. Lorence, B. J. Clark, J. M. Trant et al.
      Pages 155-163
    3. J. Doehmer, S. Dogra, M. Edigkaufer, E. Molitor, P. Siegert, T. Friedberg et al.
      Pages 164-168
  7. Immunotoxicology

    1. Front Matter
      Pages 169-169
    2. N. J. Snoeij, A. H. Penninks, W. Seinen
      Pages 171-174
    3. R. H. H. Pieters, J. Kampinga, N. J. Snoeij, M. Bol-Schoenmakers, A. W. Lam, A. H. Penninks et al.
      Pages 175-178
    4. G. F. Houben, M. H. M. Kuijpers, H. van Loveren, A. H. Penninks, E. J. Sinkeldam, W. Seinen
      Pages 183-187
  8. Carcinogenesis

    1. Front Matter
      Pages 201-201
    2. C. Hoffman, H. Bastian, M. Wiedenmann, C. Deininger, E. Eder
      Pages 219-223
    3. J. Shen, W. Kessler, B. Denk, J. G. Filser
      Pages 237-239
    4. B. Jelitto, R. R. Vangala, R. J. Laib
      Pages 246-249

About these proceedings


This supplement contains the papers submitted at EUROTOX 88, the joint Congress of the European Society of Toxicology and the Federation of the European Societies of Toxicology. The theme was one of monitoring and examining the effects of toxic substances in the biological response at the subcellular level. Mechanisms of metal carcinogenicity are discussed as well as the biomonitoring of chemical exposure. Reports are provided on the role of individual differences in man and the effect of risk assessment. Papers appear dealing with the genetic control of drug metabolizing enzymes. The role of metabolism in organic specific toxicity is discussed. Information is included on the toxicological impact of chemicals interfering with the endocrine system as well as on the effects of toxicants on the immune system. Presentations deal with the current status of risk assessment in environmental toxicology.


biomonitoring biphenyls drug environment fungicide mercury metabolism nickel pesticide pharmacokinetics polychlorinated biphenyls toxicity toxicology xenobiotic xenobiotics

Editors and affiliations

  • Philip L. Chambers
    • 1
  • Claire M. Chambers
    • 1
  • Helmut Greim
    • 2
  1. 1.Department of Pharmacology and TherapeuticsUniversity of Dublin, Trinity CollegeDublin 2Ireland
  2. 2.Institut für ToxikologieGesellschaft für Strahlen- und UmweltforschungNeuherbergWest Germany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-50336-1
  • Online ISBN 978-3-642-74117-3
  • Series Print ISSN 0171-9750
  • Buy this book on publisher's site