Oncogenes and Growth Control

  • Patricia Kahn
  • Thomas Graf

Table of contents

  1. Front Matter
    Pages I-XXIII
  2. Introduction

    1. Patricia Kahn, Thomas Graf
      Pages 1-5
  3. Growth Factors and Proto-Oncogenes in Development and Differentiation

  4. Growth Factors, Receptors, and Related Oncogenes

    1. Front Matter
      Pages 33-34
    2. Harold L. Moses, Edward B. Leof
      Pages 51-57
    3. Rik Derynck
      Pages 58-64
    4. Graham Carpenter, Linda Goodman, Lynn Shaver
      Pages 65-69
    5. Joseph Schlessinger
      Pages 77-84
    6. Hartmut Beug, Michael J. Hayman, Björn Vennström
      Pages 85-92
    7. Charles J. Sherr, E. Richard Stanley
      Pages 93-99
    8. Hidesaburo Hanafusa
      Pages 100-105
    9. Yinon Ben-Neriah, David Baltimore
      Pages 106-114
    10. Angelika Gebhardt, J. Gordon Foulkes
      Pages 115-120
    11. mos
      Donald G. Blair
      Pages 121-127
    12. Masanori Hatakeyama, Seijiro Minamoto, Hisashi Mori, Tadatsugu Taniguchi
      Pages 128-134
  5. Signal Transduction and ras Oncogenes

  6. Gene Expression and Nuclear Oncogenes

    1. Front Matter
      Pages 209-210
    2. Patrick Charnay
      Pages 211-218
    3. Uwe Schlokat, Peter Gruss
      Pages 226-234
    4. William A. Haseltine, Joseph Sodroski, Craig Rosen, Wei Chun Goh, Andrew Dayton, Daniel Celander
      Pages 247-252
    5. John Zullo, David Hall, Barrett Rollins, Charles D. Stiles
      Pages 259-263
    6. Paul D. Fahrlander, Kenneth B. Marcu
      Pages 264-270
    7. Karin Moelling
      Pages 271-277
    8. Thomas Jenuwein, Rolf Müller
      Pages 278-283
  7. Malignant Transformation as a Multistep Process

    1. Front Matter
      Pages 291-293
    2. Seng H. Cheng, William Markland, Alan E. Smith
      Pages 298-303
    3. Hartmut Land
      Pages 304-311
    4. Patricia Kahn, Achim Leutz, Thomas Graf
      Pages 312-319

About this book


How is growth controlled in normal cells? How are the growth control mechanisms perturbed in cancer cells? This book provides an up-to-date description of research aimed at resolving these questions. It is organized into four sections, each containing a series of short reviews written by experts in the field. The general headings are: growth factors, receptors, and related oncogenes: transduction of mitogenic signals and ras oncogenes; nuclear oncogenes and regulation of gene expression; and multiple steps involved in malignant transformation. The articles emphasize concepts rather than detailed facts and are intended not only for specialists in the field but also for interested readers, such as physicians and advanced students, who wish to stay abreast of developments in one of the most exciting fields in current biomedical research.


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Editors and affiliations

  • Patricia Kahn
    • 1
  • Thomas Graf
    • 1
  1. 1.European Molecular Biology LaboratoryHeidelbergGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-18760-8
  • Online ISBN 978-3-642-73325-3
  • Buy this book on publisher's site