Table of contents

  1. Front Matter
    Pages I-XX
  2. Experimental and Clinical Pharmacology

    1. Front Matter
      Pages 1-1
    2. R. A. Janis, A. V. Shrikhande, R. Greguski, M. Pan, A. Scriabine
      Pages 27-35
    3. T. Godfraind, C. Eglème, M. Finet, B. Debande, P. Jaumin
      Pages 36-44
    4. G. Ahr, W. Wingender, J. Kuhlmann
      Pages 59-66
    5. J. van Harten, P. van Brummelen, J. H. P. Wilson, D. D. Breimer
      Pages 76-79
    6. R. Joeres, G. Ahr, G. Hofstetter, H. Klinker, E. Richter
      Pages 80-84
    7. D. Scherling, G. Ahr, W. Karl
      Pages 85-88
    8. W. Klaus
      Pages 94-95
  3. Effects on Coronary Arteries: Role of Vasomotor Tone

    1. Front Matter
      Pages 97-97
    2. K. J. Beatt, P. W. Serruys, A. Soward, P. J. de Feyter, P. G. Hugenholtz
      Pages 103-108
    3. M. Schartl, C. Heidelmeyer, F. C. Dougherty, H. Schmutzler
      Pages 109-114
    4. G. Hempelmann, D. Kling, J. Boldt
      Pages 128-130
    5. C. Hirth, A. Federmann, B. Garthoff, L. Hertle, S. Kazda, J. P. Stasch
      Pages 144-150
    6. H. E. Eliahou, D. Cohen, A. Ben-David, D. Herzog, I. Serban, S. Gavendo et al.
      Pages 151-158
    7. K. Akioka, M. Kohno, T. Nishikimi, M. Teragaki, M. Yasuda, H. Oku et al.
      Pages 159-164
    8. S. Jost, W. Rafflenbeul, B. Mogwitz, U. Nellessen, H. Hecker, G. Ahr et al.
      Pages 165-170
  4. Effects on Ventricular Function

  5. Effects on Stable Angina and Ischemia

    1. Front Matter
      Pages 211-211
    2. W. Klein, D. Brandt, N. Fluch, F. Sterz
      Pages 228-232
    3. H. Reicher-Reiss, Z. Vered, U. Goldbourt, H. N. Neufeld
      Pages 233-237
    4. J. E. Creamer, J. C. O’Keefe, M. B. Maltz, S. O. Banim
      Pages 249-255
    5. W. Aschenberg, C. Nienaber, R. Spielmann, A. Fehr, A. Clausen, W. Bleifeld
      Pages 263-263
    6. J. S. Schroeder
      Pages 264-264
  6. Silent Ischemia

About these proceedings


This book, the first to provide a comprehensive overview of all studies so far carried out with this second-generation calcium entry blocker, Nisoldipine, is the fruit of a- day conference. In the first part the essential data on its experimental and clinical pharmacology are summarised by outstanding research workers in this field. The second part contains work concerning the major action of the drug, namely its effect in reducing vasomotor tone. The third part deals with intravenous or oral administration. From these data a clear profile develops, which is effective in angina pectoris of various forms and in cardiac ischaemia, both the clinically evident and the silent forms. Additionally, exploratory data in the area of cardiac failure are presented. As several contributors are based on material presented as a poster they do not contain a reference list. This book is highly recommended for all those investigators and clinicians who are researching for the optimal calcium entry blocker.


angina pectoris calcium drug heart research

Editors and affiliations

  • P. G. Hugenholtz
    • 1
  • J. Meyer
    • 2
  1. 1.Medical Faculty, ThoraxcenterErasmus University RotterdamRotterdamThe Netherlands
  2. 2.II. Med. Klinik und PoliklinikKlinikum der Universität MainzMainzGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1987
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-18394-5
  • Online ISBN 978-3-642-73010-8
  • Buy this book on publisher's site