Cardiac Valve Allografts 1962–1987

Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Subsitutes

  • A. Charles Yankah
  • Roland Hetzer
  • D. Craig Miller
  • Donald Ross
  • Jane Somerville
  • Magdi H. Yacoub
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-XVI
  2. Honorary guest lecture

  3. Procurement and preservation techniques

    1. Stephan Schüler, A. C. Yankah, R. Hetzer
      Pages 13-16
    2. Lorenzo Gonzalez-Lavin, L. McGrath, M. Alvarez, D. Graf
      Pages 17-21
    3. A. C. Yankah, R. Hetzer
      Pages 23-26
    4. S. R. May, J. G. Baust
      Pages 27-34
    5. J. K. Kirklin, J. W. Kirklin, A. D. Pacifico, S. J. Phillips
      Pages 35-36
    6. A. E. Heacox, R. T. McNally, K. G. M. Brockbank
      Pages 37-42
    7. H. L. Bank, M. K. Schmehl, K. G. M. Brockbank
      Pages 43-48
    8. D. Behrendt
      Pages 49-51
    9. F. Keller, A. C. Yankah, S. Schüler, R. Klän, G. Offermann, H. Warnecke et al.
      Pages 55-57
  4. Transplantation immunology of heart valve allografts

    1. W. Müller-Ruchholtz
      Pages 59-64
    2. Lorenzo Gonzalez-Lavin, J. Bianchi, D. Graf, S. Amini, C. I. Gordon
      Pages 69-74
    3. A. C. Yankah, H.-U. Wottge, W. Müller-Ruchholtz
      Pages 77-87
    4. H. K. Müller-Hermelink, A. C. Yankah
      Pages 89-94
    5. W. MüLLer-Ruchholtz, M. H. Yacoub
      Pages 103-106
  5. Allograft surgery of the aortic root and the ascending aorta: Transplantation techniques

  6. Reconstruction of the right ventricular outflow tract (RVOT) with allografts: Transplantation techniques

  7. Long-term results of antibiotic-treated (4 °C) allograft valves and valved conduits

    1. M. J. Elliott, R. Almeida, R. K. H. Wyse, M. R. de Leval, J. Stark
      Pages 229-235
    2. G. Fernandez, C. Deville, A. Ebner, Ch. Doutremepuich, F. Fontan
      Pages 237-247
    3. William W. Angell, J. H. Oury, J. A. Koziol, M. H. Dussault
      Pages 273-280
  8. Intermediate and long-term results of cryopreserved allografts

    1. P. E. Lange, A. Wessel, H. H. Sievers, A. C. Yankah, D. G. W. Onnasch, J. H. Bürsch et al.
      Pages 281-290
    2. James K. Kirklin, J. W. Kirklin, A. D. Pacifico, E. H. Blackstone
      Pages 291-299
    3. Armin Wessel, P. E. Lange, J. H. Bürsch, H. H. Sievers, A. C. Yankah, A. Bernhard et al.
      Pages 301-309
    4. Mark O’Brien, E. G. Stafford, M. A. H. Gardner, P. Pohlner, D. C. McGiffin, N. Johnston et al.
      Pages 311-321
    5. F. Fontan, H. Meisner
      Pages 333-343
    6. David L. Sikarskie, P. D. Stein, M. Vable
      Pages 345-346
  9. Honoray guest lecture

About these proceedings


It was the genius of Gordon Murray in Toronto that introduced the use of allografts into cardiac surgery in the 1950s. Soon after this on opposite sides ofthe world, Sir Brian Barratt-Boyes in Auckland, New Zealand, and Mr. Donald Ross in London, undertook to use allografts for the replacement of diseased aortic valves. Since that time the global interest in allografts has been patchy, episodic, and without a con­ sensus. Nonetheless, for the last 20 years at least three groups in the world have steadfastly pursued the development of new and relevant information concerning the use of allograft valves in humans. These are the centres of Sir Brian Barratt­ Boyes, Mr. Donald Ross, and Mark O'Brien in Brisbane. More recently, talented investigators, including Drs. Yankah, Yacoub, and others, have been developing information concerning the immunological aspects of the use of allografts, as well as their clinical use. No doubt, at present, cardiac valve allografts of one sort or another are the devices of choice for conduits and have an important place in the surgery of aortic valve replacement. Even so, in the mind of this writer at least, the future usefulness of allografts for the replacement of diseased cardiac valves and conduits between a ventricle and the pulmonary artery, remains problematic, and depends upon improvements in other devices for this purpose and upon improve­ ments that may be made in preparing and using allografts.


anatomy artery cardiac surgery development heart immunology surgery transplantation

Editors and affiliations

  • A. Charles Yankah
    • 1
  • Roland Hetzer
    • 1
  • D. Craig Miller
    • 2
  • Donald Ross
    • 3
  • Jane Somerville
    • 3
  • Magdi H. Yacoub
    • 4
  1. 1.Clinic for Cardiothoracic and Vascular SurgeryGerman Heart Center BerlinBerlin (West) 65Germany
  2. 2.Dept. of Cardiovascular SurgeryStanford UniversityStanfordUSA
  3. 3.National Heart HospitalLondonUK
  4. 4.Harefield HospitalNational Heart and Brompton HospitalLondonUK

Bibliographic information