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Form and Function of Mammalian Lung: Analysis by Scientific Computing

  • Andres┬áKriete

Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 145)

Table of contents

  1. Front Matter
    Pages I-IX
  2. Andres Kriete
    Pages 1-6
  3. Andres Kriete
    Pages 7-24
  4. Andres Kriete
    Pages 61-66
  5. Andres Kriete
    Pages 67-71
  6. Andres Kriete
    Pages 85-91
  7. Andres Kriete
    Pages 97-98
  8. Andres Kriete
    Pages 99-105
  9. Back Matter
    Pages 107-109

About this book

Introduction

The study approaches the investigations of airway morphology of the lung with a new set of imaging and cmputer graphical methods, including confocal imaging, computer-guided image acquisition,visualization and fractal graphics. The key result is that, in contrast to the belief that the design of the conductive part of the lung of smaller mammals can be decribed with a trumpet model, the findings reported here document a strongly monopodial branching pattern with the functional consequence of a variation of dead space between the trachea and the acini. This non-dichotomic structural design finds its continuation within the respiratory units as the necessary requirement for an optimal space filling and dense packing which cannot be achieved by a dichotomic branching only. Based on a computer model, computational physics tightly coupled with computer visualistics enables functional simulation of the lung model regarding gas transport. The predicted variance in the ventilation of acini gives rise to an explanation of the well-known difference between the morphologically predicted and physiologically required diffusion capacity.

Keywords

Computer calculus computer visualistics lung model modeling pneumology radiology visualization

Authors and affiliations

  • Andres┬áKriete
    • 1
  1. 1.Image Processing Laboratory Institute of Anatomy and Cell BiologyJustus-Liebeg-UniversityGiessenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-72220-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-64494-1
  • Online ISBN 978-3-642-72220-2
  • Series Print ISSN 0301-5556
  • Series Online ISSN 2192-7065
  • Buy this book on publisher's site