Organtransplantation in Rats and Mice

Microsurgical Techniques and Immunological Principles

  • Wolfgang Timmermann
  • Heinz-Jochen Gassel
  • Karin Ulrichs
  • Robert Zhong
  • Arnulf Thiede

Table of contents

  1. Front Matter
    Pages I-XXIII
  2. Introduction

  3. Basic Requirements for Research with Small Rodents

  4. Basic Microsurgical Techniques for Rat Organ Transplantation

    1. Front Matter
      Pages 61-61
    2. S. Timm, W. Timmermann, W. H. Hamelmann, A. Thiede
      Pages 63-67
    3. V. Lange
      Pages 69-72
    4. R. Kellersmann, H. Kiyochi, R. Black, D. Grant, R. Zhong
      Pages 83-96
    5. W. F. A. Hiller, K. Ulrichs
      Pages 97-104
    6. W. H. Hamelmann, G. Klöck, W. Timmermann
      Pages 105-111
    7. Ichiro Nakai, Takahiro Oka, David E. R. Sutherland
      Pages 113-122
    8. H.-J. Gassel, U. Steger, A. Thiede
      Pages 123-131
    9. S. Fraund, C. Mörike, G. Steinhoff
      Pages 133-140
    10. D. Meyer, H.-J. Gassel
      Pages 141-147
  5. Basic Microsurgical Techniques for Mouse Organ Transplantation

    1. Front Matter
      Pages 149-149
    2. R. Kellersmann, R. Zhong
      Pages 151-154
    3. J. Jiang, A. Humar, R. Zhong
      Pages 155-160
    4. J. Jiang, Z. Zhang, L. Chow, R. Zhong
      Pages 161-165
    5. C. J. Simeonovic, J. C. Zarb, L. S. Gazda, K. J. Lafferty, J. D. Wilson
      Pages 167-177
    6. J. Jiang, H. Wang, Q. Madrenas, R. Zhong
      Pages 179-184
    7. Z. K. Chen, S. Metcalfe
      Pages 185-192
    8. Z. Zhang, D. Grant, R. Zhong
      Pages 203-211
    9. S. Qian, F. Fu, W. Li, J. J. Fung
      Pages 213-221
  6. Immunological Concepts and Techniques

    1. Front Matter
      Pages 223-223
    2. H. J. Schlitt, S. Ko, A. Deiwick, J. Hundrieser
      Pages 285-298
    3. W. Wong, J. Fry, K. Hyde, P. Morris, K. Wood
      Pages 299-312
    4. H. Wang, P. F. Halloran
      Pages 313-324
    5. C. Otto, M. Gasser, K. Ulrichs
      Pages 325-337
    6. U. Beutner, K. Ulrichs
      Pages 339-350
  7. Vascular and Cardiac Transplantation in Rats

    1. Front Matter
      Pages 351-351
    2. T. Schang, B. von Gaudecker, A. Thiede
      Pages 353-358
    3. M. T. Menard, J. C. Madsen
      Pages 375-384
    4. R. Kellersmann, D. Grant, R. Zhong
      Pages 399-405
  8. Small Bowel Transplantation

    1. Front Matter
      Pages 407-407
    2. A. M. Gassel, A. Greiner
      Pages 417-425

About this book


Main focus of the new book will be the description and discussion of rat and mouse models for organ transplantation. Various microsurgical techniques will be presented which allow transplantation of functional organs in syngeneic systems. In particular, the extremely difficult methods necessary for organ transplantation in mice will be presented and evaluated. Besides these practical aspects the book will also cover the theoretical sides of organ transplantation like the immunobiology of allotransplantation. Special emphasis will be given to the resurgent field of xenotransplantation. The results from xenograft models developed in the recent years using rats or mice will be reviewed and their impact on future human xenotransplantation will be discussed.


Immunosuppression bone marrow liver transplantation microsurgery organ organ transplantation surgery transplantation

Editors and affiliations

  • Wolfgang Timmermann
    • 1
  • Heinz-Jochen Gassel
    • 1
  • Karin Ulrichs
    • 1
  • Robert Zhong
    • 2
  • Arnulf Thiede
    • 1
  1. 1.Chirurgische Universitätsklinik und Poliklinik WürzburgWürzburgGermany
  2. 2.Department of SurgeryUniversity of Western OntarioLondonCanada

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-72142-7
  • Online ISBN 978-3-642-72140-3
  • Buy this book on publisher's site