Table of contents

  1. Front Matter
    Pages I-XII
  2. Pharmacological Actions of Prostaglandin E1

  3. Clinical Results with Prostaglandin E1

  4. Back Matter
    Pages 111-112

About these proceedings


Prostaglandins were discovered in the early 1930s following research into their extremely potent biological effects. During the last decade especially two com­ pounds sharing the same receptor on the platelet surface, the antiaggregatory prostaglandins PGE and PGI , attracted considerable interest in cardiovascular 1 2 medicine. Since 1973 PGE has been widely used in the therapy of peripheral vascular 1 disease. Although its effects on platelet function, smooth muscle cells, vascular wall cell lipid metabolism, red cell deformability and plasmatic coagulation are well known, these factors altogether do not fully explain the efficacy of PG El in the therapy of advanced atherosclerosis. This book is the outcome of a workshop organised by Schwarz GmbH (Mon­ heim, FRG) which was held at Stresa, Italy, in April 1986. The coming together of researchers and clinicians produced a survey of the chemistry, physiology, pharmacology and clinical efficacy of PGE which will serve as a new insight 1 into the complexity of basic and clinical applications of PGE • 1 Helmut Sinzinger Waltraud Rogatti Table of Contents Pharmacological Actions of Prostaglandin E.


atherosclerosis cardiovascular metabolism physiology platelet

Editors and affiliations

  • Helmut Sinzinger
    • 1
  • Waltraud Rogatti
    • 2
  1. 1.Atherosclerosis Research GroupUniversity of ViennaWienAustria
  2. 2.Sanol Schwarz GmbHMonheimFederal Republic of Germany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-17240-6
  • Online ISBN 978-3-642-71679-9
  • Buy this book on publisher's site