Fibrin Sealant in Operative Medicine

Volume 5: Thoracic Surgery — Cardiovascular Surgery

  • Günther Schlag
  • Heinz Redl
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-XVIII
  2. Principles of Fibrin Sealing

  3. Thoracic Surgery

    1. Front Matter
      Pages 61-61
    2. D. Grunenwald, P. R. Vouhe, J. Y. Neveux
      Pages 63-65
    3. D. Grunenwald, P. R. Vouhe, J. Y. Neveux
      Pages 66-67
    4. T. M. Orlowski, J. Kolodziej, J. Domagala
      Pages 68-75
    5. F. Eckersberger, E. Moritz, E. Wolner
      Pages 82-88
    6. M. Spiegel, J. Benesch, R. Siebenmann
      Pages 95-101
    7. N. Pridun, W. Heindl, H. Redl, G. Schlag, E. Machacek
      Pages 121-125
    8. E. D. Kreuser, E. Seifried, R. Hartmann
      Pages 130-136
    9. J. Boese-Landgraf, R. Häring, B. Semsch
      Pages 137-140
  4. Cardiovascular Surgery

    1. Front Matter
      Pages 141-141
    2. S. Eufrate, P. Pugliese, R. Moschetti, L. Scebba, F. Veschi
      Pages 143-147
    3. P. Fundarò, A. R. Velardi, C. Santoli
      Pages 152-154
    4. M. T. Corfitsen, B. Paaschburg Nielsen, S. Juul Jørgensen
      Pages 155-158
    5. K. H. Tscheliessnigg, W. Stenzl, B. Rigler, J. Kraft-Kinz
      Pages 176-180
    6. W. Stenzl, K. H. Tscheliessnigg, D. Dacar, F. Iberer, B. Rigler
      Pages 181-184
    7. A. Haverich, T. Wahlers, G. Walterbusch, H. G. Borst
      Pages 185-190
    8. G. Vercellio, M. Coletti, G. Agrifoglio
      Pages 196-200
    9. J. Sadowski, A. Dziatkowiak, R. Pfitzner, W. Tracz, B. Kapelak, K. Traczyński
      Pages 201-204
    10. W. Simma, H. Hesse
      Pages 205-208
    11. R. P. Franke, U. Dauer, W. Müllners, R. Fuhrmann, C. Mittermayer
      Pages 209-215
  5. Back Matter
    Pages 217-218

About these proceedings


Fibrin plays a prominent role in wound healing. It has a hemostatic effect, induces cellular response to wound damage, and, by forming strands to build a matrix, assists in neovascularization and fibroblast proliferation. The concept of using clotting substances from human blood for wound manage­ ment and to achieve hemostasis in bleeding parenchymatous organs can be traced to 1909, when Bergel [1] reported on the hemostatic effect of fibrin powder. In 1915, Grey [3] employed fibrin to control bleeding in neurosurgical operations of the brain. A year later, Harvey [4] used fibrin patches to stop bleeding from parenchy­ matous organs in general surgery. It took more than two decades for this ingenious idea to be rediscovered. In 1940, Young and Medawar [8] reported on experimental nerve anastomosis by sealing. Similarly, Tarlov and Benjamin [7] reunited nerves with plasma clots in 1943. Tarlov improved the results obtained with clot anastomosing of nerves by avoiding tension at the nerve stumps. In 1944, Cronkite et al. [2] reported on an initial series of eight cases in which fibrinogen and thrombin had been used successfully for anchoring skin grafts.


aneurysm blood brain bypass cardiac surgery general surgery heart lung medicine plasma proliferation skin surgery thoracic surgery vascular surgery

Editors and affiliations

  • Günther Schlag
    • 1
  • Heinz Redl
    • 1
  1. 1.Ludwig-Boltzmann-Institut für experimentelle TraumatologieViennaAustria

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-17141-6
  • Online ISBN 978-3-642-71633-1
  • Buy this book on publisher's site