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The Wild Mouse in Immunology

  • Michael Potter
  • Joseph H. Nadeau
  • Michael P. Cancro

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 127)

Table of contents

  1. Genes Determining Resistance and Susceptibility to Infections

  2. Retroviral Genes

    1. Front Matter
      Pages 347-347
    2. C. A. Kozak, R. R. O’Neill
      Pages 349-353
    3. D. Gallahan, C. Escot, E. Hogg, R. Callahan
      Pages 354-361
    4. R. Callahan, D. Gallahan, L. A. D’Hoostelaere, M. Potter
      Pages 362-370
  3. List of Wild Mouse Stocks and Sources

About these proceedings

Introduction

The present volume of "Current Topics in Microbiology and Immunology" is a series of papers on subjects that are relevant to the growing use of 'wild mice' in immunological, microbiological and genetical research. 'Wild mice' is a jargonistic term that is used chiefly in the laboratory to refer to the naturally living forms of house mice (Mus musculus) and also other species closely related to M. musculus. This group of species is designated by systematists as the genus Mus. Immunologists began 20 years ago to study the polymorphisms of 1mmunoglobulins and major histocompatibility complex antigens in wild mice. An extrordinary extension of the highly polymorphic array of phenotypes known in inbred mice was encountered. Breeding stocks of wild mice were brought into the laboratory. This included not only M. musculus but a)so many of the available species in the genus Mus-from Southeast Asia ~nd Europe. This availability led to other comparisons of 'wild' and inbred mice and the discovery of other new and interesting phenotypes and genotypes. It became apparent that inbred strains of mice provided only a limited window for viewing the genetic diversity of Mus musculus.

Keywords

antigen histocompatibility immunology microbiology

Editors and affiliations

  • Michael Potter
    • 1
  • Joseph H. Nadeau
    • 2
  • Michael P. Cancro
    • 3
  1. 1.Laboratory of Genetics, National Institutes of HealthNational Cancer InstituteBethesdaUSA
  2. 2.The Jackson LaboratoryBar HarborUSA
  3. 3.School of Medicine, Department of PathologyUniversity of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-71304-0
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-71306-4
  • Online ISBN 978-3-642-71304-0
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site