New Aspects in Regional Anesthesia 4

Major Conduction Block: Tachyphylaxis, Hypotension, and Opiates

  • Hans Joachim Wüst
  • M. d’Arcy Stanton-Hicks
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-XV
  2. Tachyphylaxis in Long-Term Epidural Analgesia

    1. Front Matter
      Pages 1-1
    2. P. P. Raj, D. D. Denson, R. H. De Jong
      Pages 10-19
    3. D. B. Scott
      Pages 20-23
    4. M. d’Arcy Stanton-Hicks, H. J. Wüst, U. Koch, D. Weidlich, I. Düffel
      Pages 32-38
    5. Hans Joachim Wüst, M. d’Arcy Stanton-Hicks
      Pages 46-49
  3. Hypotension Induced by Major Conduction Blocks

  4. Epidural and Intrathecal Opioids in Acute and Chronic Pain Treatment

    1. Front Matter
      Pages 111-111
    2. R. A. Boas, J. W. Villinger
      Pages 113-121
    3. C. B. Devaux, P. Freger, J. Godlewski
      Pages 122-127
    4. N. Rawal, K. Möllefors, M. Wattwil, K. Axelsson, G. Lingardh, B. Widman
      Pages 135-139
    5. B. J. Kraynack, L. Moore, E. F. Klein
      Pages 140-144
    6. A. van Steenberge
      Pages 145-148
    7. H. Müller, W. Vogelsberger, K. Aigner, I. Gerlach, G. Hempelmann
      Pages 149-157
  5. Back Matter
    Pages 159-165

About these proceedings


Major conduction blocks utilizing local anesthetics or opiates are find­ ing ever increasing applications in daily routine. However, two serious drawbacks are associated with their use: hypotension during surgery and the development of tolerance in long-term epidural analgesia. When opiates are injected epidurally or intrathecally, numerous side effects such as itching, nausea and vomiting, or respiratory depression have been reported. The pathophysiology of complications arising during a major conduction block and measures to prevent them were discussed by 19 experts at the 4th International Symposium at DUsseldorf. This volume contains 21 papers presented on three topics: 1. tachyphylaxis in long-term epidural anesthesia, 2. hypotension due to epidural and spinal anesthesia, and 3. effects and dangers of epidural and intrathecal opiates. With regard to the safety of our patients during anesthesia, current practices of preventing complications were evaluated, and preliminary guidelines for a more rational approach toward prevention and treat­ ment based on a knowledge of pathophysiologic mechanisms were developed. It is our hope that the anesthesiologist will profit from the discussion of regional anesthesia contained in this volume, many aspects of which have never before been presented in such detail.


Opiate complications pain pathophysiology prevention surgery

Editors and affiliations

  • Hans Joachim Wüst
    • 1
  • M. d’Arcy Stanton-Hicks
    • 2
  1. 1.Department of AnesthesiologyUniversity HospitalDüsseldorfGermany
  2. 2.Department of AnesthesiologyUniversity of Colorado H.S.C.DenverUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-15938-4
  • Online ISBN 978-3-642-70807-7
  • Series Print ISSN 0171-1814
  • Buy this book on publisher's site