Senile Dementia of the Alzheimer Type

Early Diagnosis, Neuropathology and Animal Models

  • Jörg Traber
  • Willem Hendrik Gispen
Conference proceedings

Part of the Advances in Applied Neurological Sciences book series (NEUROLOGICAL, volume 2)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Early Diagnosis of Senile Dementia of the Alzheimer Type

    1. Front Matter
      Pages 1-1
    2. Behavioral and Clinical Aspects

      1. C. Flicker, S. H. Ferris, T. Crook, R. T. Bartus, B. Reisberg
        Pages 2-17
      2. R. C. Mohs, B. S. Greenwald, D. D. Dunn, K. L. Davis
        Pages 38-43
      3. S. Kanowski, H. Krüger, K.-P. Kühl
        Pages 44-59
      4. J. R. M. Copeland, M. E. Dewey
        Pages 72-83
    3. Brain Tissue Parameters

      1. W. L. Curati, R. E. Steiner
        Pages 117-123
      2. R. P. Friedland, T. F. Budinger, W. J. Jagust, E. Koss, S. Derenzo, R. H. Huesman et al.
        Pages 124-133
      3. W.-D. Heiss, G. Pawlik, K. Herholz, B. Szelies, C. Beil, K. Wienhard
        Pages 134-147
  3. Novel Developments in the Neuropathology of Senile Dementia of the Alzheimer Type

    1. Front Matter
      Pages 149-149
    2. J. P. Brion, P. van den Bosch de Aguilar, J. Flament-Durand
      Pages 164-174
    3. P. J. Whitehouse, K.-S. Au
      Pages 175-182
    4. J. M. Candy, J. A. Edwardson, J. Klinowski, A. E. Oakley, E. K. Perry, R. H. Perry
      Pages 183-197
    5. B. H. Anderton, M. C. Haugh, J. Kahn, C. Miller, A. Probst, J. Ulrich
      Pages 205-216
  4. Brain Plasticity and Trophic Factors

    1. Front Matter
      Pages 217-217
    2. S. H. Appel, K. Ojika, Y. Tomozawa, R. Bostwick
      Pages 218-230
    3. P. M. Edwards, W. H. Grispen
      Pages 231-240
    4. S. Hoyer, L. Frölich
      Pages 241-248
  5. Animal Models

  6. Back Matter
    Pages 367-376

About these proceedings


Society is showing increasing concern for disorders related to aging that lead to a loss of brain function. In view of the enormous proportion of elderly people in our society today, brain aging is more than ever subject to challenge to us all, not only politicians and health authorities, but every individual who is confronted with the difficult situation of watching the mental powers of apparently healthy elderly friends, neighbours, or relatives fail, often with alarming rapidity. This challenge is directed especially toward us scientists. As one of our colleagues succinctly put it 2 years ago at the close of our First International Symposium on Brain Aging: "Do something. We are not dealing here with just another disease; we are concerned with human dignity. " More than any statistics, these words convinced me that Tropon's decision to leave the field of classic CNS pharmacology and move into the field of gerontopsychopharmacology was the right one, even though we knew that success would be uncertain and that, even if it finally comes it will be many years hence. At this point, let me add a personal comment: each one of us is judged by his or her own success. We live in a competitive society where success counts. This applies not only to the businessman, but also to the scientist, in particular, to those in industry.


Alzheimer's disease Alzheimer´s disease Parkinson Staging brain cognition dementia depression electroencephalography (EEG) neuroanatomy neurons neuropathology neuropharmacology nuclear magnetic resonance (NMR) pathology

Editors and affiliations

  • Jörg Traber
    • 1
  • Willem Hendrik Gispen
    • 2
  1. 1.Neurobiology DepartmentTroponwerke GmbH & Co. KGKöln 80Germany
  2. 2.Division of Molecular Neurobiology Rudolf Magnus Institute for Pharmacology and Institute of Molecular BiologyState University of UtrechtUtrechtThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1985
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-70646-2
  • Online ISBN 978-3-642-70644-8
  • Series Print ISSN 0935-0195
  • Buy this book on publisher's site