In Vitro Effects of Mineral Dusts

Third International Workshop

  • Ernst G. Beck
  • Jean Bignon

Part of the NATO ASI Series book series (volume 3)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. Introduction

  3. Minerals and Target Cells

    1. Front Matter
      Pages 7-7
    2. Role of Physicochemical Properties of Minerals

      1. G. L. Fisher, K. L. McNeill, B. T. Mossman, J. Marsh, A. R. McFarland, R. W. Hart
        Pages 31-38
    3. Cellular Effects of Mineral Dusts

  4. Immune Responses and Immunotoxicity

    1. Front Matter
      Pages 107-107
    2. R. P. Daniele
      Pages 109-119
    3. D. B. Warheit, G. George, L. H. Hill, R. Snyderman, A. R. Brody
      Pages 129-138
    4. J. Stankova, S. Gouin, R. Bégin, M. Rola-Pleszczynski
      Pages 139-147
    5. V. Vallyathan, N. Hahon, J. Booth, D. Schwegler, M. Sepulveda
      Pages 159-165
  5. Carcinogenicity and Related Genotoxic Events

    1. Front Matter
      Pages 169-169
    2. J. C. Barrett
      Pages 171-176
    3. D. G. Ririe, T. W. Hesterberg, J. C. Barrett, P. Nettesheim
      Pages 177-184
    4. J. F. Lechner, T. Tokiwa, H. Yeager Jr., C. C. Harris
      Pages 197-202
    5. M. J. Patérour, A. Renier, J. Bignon, M. C. Jaurand
      Pages 203-207
    6. J. Tobaly, M. Sallé, M. Patérour, M. C. Jaurand, J. Bignon, R. Ravicovitch-Ravier
      Pages 209-214
    7. S. A. Hubbard, T. McDonald, C. M. Hunt, J. W. Bridges
      Pages 247-252
    8. F. Denizeau, M. Marion, J. Fleury, G. Chevalier, M. G. Côté
      Pages 261-265
  6. Effects of Mineral Dusts on Cell Metabolism in Relation to Inflammation and Fibrogenesis

    1. Front Matter
      Pages 281-281
    2. Synthesis and Release of Mediators

      1. S. Kouzan, P. Nettesheim, T. Eling, A. R. Brody
        Pages 291-295
      2. K. B. Adler, G. B. Butler, D. R. Hemenway, J. E. Schwarz, P. O. Banks, J. N. Evans
        Pages 297-303
      3. R. C. Brown, A. Poole, N. F. Johnson
        Pages 313-319
    3. Other Effects and Fibrogenesis

      1. J. D. Brain, B. D. Beck
        Pages 323-335
      2. R. Davies, G. Erdogdu, R. J. Hill, J. H. Edwards
        Pages 353-358
      3. R. Bégin, S. Massé, M. Rola-Pleszczynski, G. Drapeau, S. Péloquin, M. Geoffrey et al.
        Pages 359-367

About this book


The Third International \~orkshop on "The in Vitro Effects of Mineral Dusts" was held on October 1 - 4, 1984 in Schluchsee, Black Forest, Federal Republic of Germany. In six sessions, 93 participants from 14 countries (USA 32, France 17, United Kingdom 12, FRG 11, Canada 9, Belgium 3, Hungary 1, Italy 2, India 1, Nether­ lands 1, Norway 1, Poland 1, Portugal 1, Turkey 1) treated and discussed the following subjects: - Significance of the physico-chemical properties of inhalable mineral dusts (mine dusts, asbestos, Man-Made Mineral Fibres - MMMF). - Cellular effects of inhalable mineral dusts with special regard to target ce 11 s. - Immune response and immune toxicity. - Carcinogenicity and interrelated genotoxic and non-genotoxic effects. - Effect of cell metabolism in combination with inflammation and fibrogenesis. - Significance and credibility of in vitro test systems. For the pathogenesis of biological effects and diseases caused by inhalable mineral dusts a number of factors may be significant such as: - Type of dust - Dose of dust - Size and shape of dust particles, and especially - Surface properties of dust particles, which inter alia determine the - sorption properties, e.g. for environmental substances.


Dusts Minerals cell environment forest immune response metabolism pathogenesis

Editors and affiliations

  • Ernst G. Beck
    • 1
  • Jean Bignon
    • 2
  1. 1.Hygiene-InstitutUniversität GießenGießenGermany
  2. 2.Unité INSERMCHU Henri MondorCreteil CedexFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1985
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-70632-5
  • Online ISBN 978-3-642-70630-1
  • Buy this book on publisher's site