Highlights in Asthmology

1. Immunology

   1. Delayed-type Hypersensitivity Responses to Inhalant Allergens: a Form of Cutaneous Basophil Hypersensitivity (CBH)

      • E. B. Mitchell

      Pages 147-151

2. Mediator Release and Bronchial Obstruction

   1. Front Matter

      Pages 153-153

      PDF

   2. Physiological and Pharmacological Control of Inflammatory Mediator Release in Bronchial Asthma

      • S. T. Holgate

      Pages 155-166

   3. Mast Cells and Basophils

      • S. P. Peters, J. A. Grant, A. M. Dvorak, L. M. Lichtenstein

      Pages 167-185

   4. Alveolar Macrophages

      • Ph. Godard, M. Damon, Ph. Vago

      Pages 186-194

   5. Neutrophils and the Asthmatic Response

      • A. B. Kay

      Pages 195-200

   6. Eosinophils in Bronchial Asthma

      • E. Frigas, G. J. Gleich

      Pages 201-211

   7. Mediators of Asthma Derived from Arachidonic Acid

      • R. A. Lewis, J.-L. Robin

      Pages 212-220

   8. PAF-acether (Platelet Activating Factor)

      • B. Arnoux, C. Brink, J. Benveniste

      Pages 221-227

   9. Immediate-type Reactions

      • B. Zweiman, P. C. Atkins

      Pages 228-236

   10. Late Phase Reactions

       • W. Dorsch

       Pages 237-251

3. Bronchial Pathophysiology

   1. Front Matter

      Pages 253-253

      PDF

   2. Bronchi of Asthmatic Patients

      • Ph. Godard, Y. Maria, F. B. Michel

      Pages 255-259

   3. The Site of Bronchial Obstruction in Asthma

      • Ch. Préfaut

      Pages 260-264

   4. Factors in Bronchial Hyperreactivity

      • H. A. Boushey

      Pages 265-275

   5. Bronchial Hyperreactivity: Autonomic Nervous System Abnormalities

      • M. A. Kaliner

      Pages 276-284

   6. Bronchial Hyperresponsiveness and Asthma: Unanswered Questions

      • J. Orehek

      Pages 285-289

4. Asthma due to Allergy Occupation, Food and Drugs

   1. Front Matter

      Pages 291-291

      PDF

   2. Preparation and Stability of Pollen Extracts

      • H. Baer, M. C. Anderson

      Pages 293-296

   3. Allergen Standardization

      • R. A. Goldstein

      Pages 297-300

F. B. Michel Asthmology is the neologism I suggested for ideas which were acceptable at the begin­ the title of a book published in 1981 on ning of the 20th century, and in particular bronchial asthma [4,5]. to Pasteur's concept of "one cause, one ill­ ness", many syndromes like high blood Among a certain number of scientific pressure or asthma are the result of the publications on this subject, it is one of the overlapping of hereditary factors and ac­ few suggestions that I have the weakness to quired factors. This is one reason why asth­ feel somewhat proud of. In fact, this word has had the career I hoped it would and, ma is not really an illness in the real sense judging by the frequency with which it is of the word but, a clinical and functional respiratory syndrome [1]. used in both written and spoken language, it did answer a need. I had no intention of The innate, the "terrain", transmitted by suggesting one more neologism but it heredity, can possibly concern two factors: seemed to me that the word asthmology The bronchial hyperreactivity factor (BHR), had an element of novelty and, above all, is often present in early childhood and its produced the necessary awareness of the reality is a result of the studies of large need to bring together, within a kind of groups of homo- and heterozygotic twins.

• allergy
• antibody
• asthma
• bacteria
• blood
• bronchial asthma
• childhood
• diseases
• immunology
• language
• lymphocytes
• macrophages
• pathophysiology
• pharmacology
• physiology

• Clinique des Maladies Respiratoires, Hôpital de l’Aiguelongue, Montpellier Cédex, France

  François Bernard Michel, Jean Bousquet, Philippe Godard

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