Renal Pathology in Biopsy

Light, Electron and Immunofluorescent Microscopy and Clinical Aspects

  • Hans Ulrich Zollinger
  • Michael Jörg Mihatsch

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Technique and General Pathology

    1. Front Matter
      Pages XV-XV
    2. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 1-4
    3. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 5-7
    4. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 8-20
    5. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 21-45
    6. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 46-53
    7. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 54-115
    8. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 116-117
    9. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 118-138
    10. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 139-146
    11. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 147-154
    12. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 155-172
  3. Histopathology of Specific Renal Disease States

    1. Front Matter
      Pages 175-175
    2. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 177-187
    3. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 188-281
    4. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 282-310
    5. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 311-316
    6. Hans Ulrich Zollinger, Michael Jörg Mihatsch
      Pages 317-366

About this book

Introduction

Vor die Therapie setzten die Gotter die Diagnose. Otto NiigeJi Renal biopsy has decisively enriched renal diagnostics. Kidney diseases may be monitored during their entire course, and new techniques - such as immunofluorescence and electron microscopy - may be systematically applied, resulting in novel insights into the morphogenesis, pathogenesis, and etiology of kidney lesions. These insights, in turn, have served as new starting points, in the spirit of the quotation above, for the institution of causal therapy by the clinician. This work presents our findings based on 20 years of experience in evaluating renal biopsies. As of the end of 1974, our computer-supported, systematic clinical, morphologic, and follow-up evaluation of case material consisted of over 2000 biopsies, including 679 examined by electron microscopy and 400 by immunofluorescence microscopy. The subsequent 500 biopsies (400 studied by electron microscopy and 300 by immunofluorescence) were con­ sidered qualitatively only. In order to enhance qualitative findings with quantitative data, it was necessary to devise new methods for quantifying electron-microscopic findings. Additionally, we attempted to correlate cyto­ logic and immunofluorescent observations to integrate the isolated findings of electron microscopy into a vital cytologic pattern of reactions. We also attempted to evaluate the almost overwhelming flood of publications, especially those appearing within the last 10 years. The idea for this book was conceived a decade ago. At that time, however, our own experience in renal biopsy diagnostics seemed insufficient to sup­ port such a major undertaking.

Keywords

Electron micrographs Kidney punctate Nierenerkrankung biopsy carcinoma cell diagnostics differential diagnosis electron microscopy genetics histology histopathology pathogenesis pathology tissue

Authors and affiliations

  • Hans Ulrich Zollinger
    • 1
  • Michael Jörg Mihatsch
    • 1
  1. 1.Institut für Pathologie der Universität BaselBaselSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-66731-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1978
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-66733-6
  • Online ISBN 978-3-642-66731-2
  • About this book